ABIN360055

antibody from antibodies-online

Targeting: FKBP1A FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN360055

Provider

antibodies-online

Product name

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (Middle Region) antibody

Antibody type

Polyclonal

Description

Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Reactivity

Human

Host

Rabbit

Epitope

Middle Region

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T.

Gerard M, Debyser Z, Desender L, Baert J, Brandt I, Baekelandt V, Engelborghs Y
Journal of neurochemistry 2008 Jul;106(1):121-33

---

A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis.

Shor B, Zhang WG, Toral-Barza L, Lucas J, Abraham RT, Gibbons JJ, Yu K
Cancer research 2008 Apr 15;68(8):2934-43

---

FK506 binding protein associated with the calcium release channel (ryanodine receptor).

Jayaraman T, Brillantes AM, Timerman AP, Fleischer S, Erdjument-Bromage H, Tempst P, Marks AR
The Journal of biological chemistry 1992 May 15;267(14):9474-7