27248-1-AP

antibody from Proteintech Group

Targeting: RICTOR AVO3, KIAA1999, MGC39830, PIA

Provider product page for 27248-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [21]
Comments [0]
Validations [0]

Submit

Product number: 27248-1-AP - Provider product page
Provider: Proteintech Group
Product name: RICTOR antibody
Antibody type: Polyclonal
Description: KD/KO validated RICTOR antibody (Cat. #27248-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

RICTOR protein structure - 27248-1-AP shown in red.

Submitted references Macropinocytic cups function as signal platforms for the mTORC2-AKT pathway to modulate LPS-induced cytokine expression in macrophages.

Wang L, Sun X, Chen J, Li Y, He Y, Wei J, Shen Z, Yoshida S
Journal of leukocyte biology 2024 Oct 1;116(4):738-752

BMP9 induces osteogenic differentiation through up-regulating LGR4 via the mTORC1/Stat3 pathway in mesenchymal stem cells.

Zhang J, Jiang J, Liu H, Wang S, Ke K, Liu S, Jiang Y, Liu L, Gao X, He B, Su Y
Genes & diseases 2024 May;11(3):101075

Diterpenoid tanshinones inhibit gastric cancer angiogenesis through the PI3K/Akt/mTOR signaling pathway.

Yu JR, Liu YY, Gao YY, Qian LH, Qiu JL, Wang PP, Zhang GJ
Journal of ethnopharmacology 2024 Apr 24;324:117791

FARSB Facilitates Hepatocellular Carcinoma Progression by Activating the mTORC1 Signaling Pathway.

Wang Y, Wang G, Hu S, Yin C, Zhao P, Zhou X, Shao S, Liu R, Hu W, Liu GL, Ke W, Song Z
International journal of molecular sciences 2023 Nov 24;24(23)

Identification of circular dorsal ruffles as signal platforms for the AKT pathway in glomerular podocytes.

Hua R, Wei J, Torres M, He Y, Li Y, Sun X, Wang L, Inoki K, Yoshida S
Journal of cellular physiology 2023 May;238(5):1063-1079

Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways.

Yasuda T, Ishihara T, Ichimura A, Ishihara N
Cell reports 2023 May 30;42(5):112434

Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.

Li X, Wang W, Hou Y, Li G, Yi H, Cui S, Zhang J, He X, Zhao H, Yang Z, Qiu Y, Liu Z, Xie J
Ecotoxicology and environmental safety 2023 Jun 1;257:114914

Interleukin 6 promotes BMP9-induced osteoblastic differentiation through Stat3/mTORC1 in mouse embryonic fibroblasts.

Wang SY, Jiang JH, Liu SY, Zhang J, Gao X, Liu H, Ke KX, Jiang Y, Liu L, He BC
Aging 2023 Feb 1;15(3):718-733

A cleaved METTL3 potentiates the METTL3-WTAP interaction and breast cancer progression.

Yan C, Xiong J, Zhou Z, Li Q, Gao C, Zhang M, Yu L, Li J, Hu MM, Zhang CS, Cai C, Zhang H, Zhang J
eLife 2023 Aug 17;12

iPSC-sEVs alleviate microglia senescence to protect against ischemic stroke in aged mice.

Niu X, Xia Y, Luo L, Chen Y, Yuan J, Zhang J, Zheng X, Li Q, Deng Z, Wang Y
Materials today. Bio 2023 Apr;19:100600

Spiropachysine A suppresses hepatocellular carcinoma proliferation by inducing methuosis in vitro and in vivo.

Fang Y, Zhong T, Yang L, Luo F, Li Q, Wang D, Li Q, Fan Y, Yang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154151

PCB153 suppressed autophagy via PI3K/Akt/mTOR and RICTOR/Akt/mTOR signaling by the upregulation of microRNA-155 in rat primary chondrocytes.

Liu Z, Huang Y, Jin X, Liu L, Gu H
Toxicology and applied pharmacology 2022 Aug 15;449:116135

Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-mediated Effects on mTORC1 and mTORC2.

Fu Y, Wei Y, Zhou Y, Wu H, Hong Y, Long C, Wang J, Wu Y, Wu S, Shen L, Wei G
Endocrinology 2021 Oct 1;162(10)

Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.

Sun Z, Zhang L, Li L, Shao C, Liu J, Zhou M, Wang Z
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380

A glycolytic shift in Schwann cells supports injured axons.

Babetto E, Wong KM, Beirowski B
Nature neuroscience 2020 Oct;23(10):1215-1228

TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.

Song S, Qiu D, Wang Y, Wei J, Wu H, Wu M, Wang S, Zhou X, Shi Y, Duan H
Experimental cell research 2020 Mar 15;388(2):111862

Rapamycin promotes endothelial-mesenchymal transition during stress-induced premature senescence through the activation of autophagy.

Sasaki N, Itakura Y, Toyoda M
Cell communication and signaling : CCS 2020 Mar 12;18(1):43

Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.

Song S, Qiu D, Shi Y, Wang S, Zhou X, Chen N, Wei J, Wu M, Wu H, Duan H
Journal of cellular physiology 2019 Sep;234(9):16485-16502

mTOR-S6K1 pathway mediates cytoophidium assembly.

Sun Z, Liu JL
Journal of genetics and genomics = Yi chuan xue bao 2019 Feb;46(2):65-74

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

Tang W, Zhou W, Xiang L, Wu X, Zhang P, Wang J, Liu G, Zhang W, Peng Y, Huang X, Cai J, Bai Y, Bai L, Zhu W, Gu H, Xiong J, Ye C, Li A, Liu S, Wang J
Nature communications 2019 Feb 8;10(1):663

Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis, Endothelial Dysfunction, and Corporal Fibrosis.

Lin H, Wang T, Ruan Y, Liu K, Li H, Wang S, Li M, Liu J
The journal of sexual medicine 2018 Sep;15(9):1246-1259

No comments: Submit comment

No validations: Submit validation data