Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 17673-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17673-1-AP, RRID:AB_2215504
- Product name
- VPS4A/B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated VPS4A/B antibody (Cat. #17673-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Improved VPS4B O-GlcNAc modification triggers lipid droplets transferring from adipocytes to nasopharyngeal carcinoma cells.
Salvianolic Acid B Attenuates Liver Fibrosis via Suppression of Glycolysis-Dependent m1 Macrophage Polarization.
Autophagic extracellular vesicles (AEVs) are distinct from exosomes and play crucial roles in viral infections.
Amino acid deprivation in cancer cells with compensatory autophagy induction increases sensitivity to autophagy inhibitors.
VPS4B orchestrates response to nuclear envelope stress by regulating ESCRT-III dynamics in glioblastoma.
Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy.
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis.
Characterization of Bovine Foamy Virus Gag Late Assembly Domain Motifs and Their Role in Recruiting ESCRT for Budding.
His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation.
RAB31 marks and controls an ESCRT-independent exosome pathway.
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes.
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration.
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
Yin H, Shan Y, Zhu Q, Yuan L, Ju F, Shi Y, Han Y, Wu R, Xia T, Zhang K, You Y, You B
Cancer & metabolism 2025 May 23;13(1):24
Cancer & metabolism 2025 May 23;13(1):24
Salvianolic Acid B Attenuates Liver Fibrosis via Suppression of Glycolysis-Dependent m1 Macrophage Polarization.
Song H, Li ZW, Xu W, Tan Y, Kuang M, Pei G, Wang ZQ
Current issues in molecular biology 2025 Jul 29;47(8)
Current issues in molecular biology 2025 Jul 29;47(8)
Autophagic extracellular vesicles (AEVs) are distinct from exosomes and play crucial roles in viral infections.
Mao K, Huo F, Wei H, Wang F, Xiong S, Fu Y
Nature communications 2025 Dec 21;17(1):1095
Nature communications 2025 Dec 21;17(1):1095
Amino acid deprivation in cancer cells with compensatory autophagy induction increases sensitivity to autophagy inhibitors.
Fukui T, Yabumoto M, Nishida M, Hirokawa S, Sato R, Kurisu T, Nakai M, Hassan MA, Kishimoto K
Molecular & cellular oncology 2024;11(1):2377404
Molecular & cellular oncology 2024;11(1):2377404
VPS4B orchestrates response to nuclear envelope stress by regulating ESCRT-III dynamics in glioblastoma.
Wu Z, Omura I, Saito A, Imaizumi K, Kamikawa Y
Nucleus (Austin, Tex.) 2024 Dec;15(1):2423660
Nucleus (Austin, Tex.) 2024 Dec;15(1):2423660
Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy.
Nozawa T, Toh H, Iibushi J, Kogai K, Minowa-Nozawa A, Satoh J, Ito S, Murase K, Nakagawa I
Nature communications 2023 Oct 6;14(1):6230
Nature communications 2023 Oct 6;14(1):6230
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis.
Lee YJ, Shin KJ, Jang HJ, Ryu JS, Lee CY, Yoon JH, Seo JK, Park S, Lee S, Je AR, Huh YH, Kong SY, Kwon T, Suh PG, Chae YC
Developmental cell 2023 Feb 27;58(4):320-334.e8
Developmental cell 2023 Feb 27;58(4):320-334.e8
Characterization of Bovine Foamy Virus Gag Late Assembly Domain Motifs and Their Role in Recruiting ESCRT for Budding.
Wang Z, Li R, Liu C, Qiao W, Tan J
Viruses 2022 Mar 3;14(3)
Viruses 2022 Mar 3;14(3)
His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation.
Parkinson G, Roboti P, Zhang L, Taylor S, Woodman P
Journal of cell science 2021 Nov 1;134(21)
Journal of cell science 2021 Nov 1;134(21)
RAB31 marks and controls an ESCRT-independent exosome pathway.
Wei D, Zhan W, Gao Y, Huang L, Gong R, Wang W, Zhang R, Wu Y, Gao S, Kang T
Cell research 2021 Feb;31(2):157-177
Cell research 2021 Feb;31(2):157-177
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G
Journal of extracellular vesicles 2020;9(1):1716513
Journal of extracellular vesicles 2020;9(1):1716513
ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes.
Larios J, Mercier V, Roux A, Gruenberg J
The Journal of cell biology 2020 Mar 2;219(3)
The Journal of cell biology 2020 Mar 2;219(3)
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Mercier V, Larios J, Molinard G, Goujon A, Matile S, Gruenberg J, Roux A
Nature cell biology 2020 Aug;22(8):947-959
Nature cell biology 2020 Aug;22(8):947-959
Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration.
Wang H, Wang X, Zhang K, Wang Q, Cao X, Wang Z, Zhang S, Li A, Liu K, Fang Y
Science advances 2019 Feb;5(2):eaav4971
Science advances 2019 Feb;5(2):eaav4971
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
Schwenk BM, Hartmann H, Serdaroglu A, Schludi MH, Hornburg D, Meissner F, Orozco D, Colombo A, Tahirovic S, Michaelsen M, Schreiber F, Haupt S, Peitz M, Brüstle O, Küpper C, Klopstock T, Otto M, Ludolph AC, Arzberger T, Kuhn PH, Edbauer D
The EMBO journal 2016 Nov 2;35(21):2350-2370
The EMBO journal 2016 Nov 2;35(21):2350-2370
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VPS4B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human VPS4B. This antibody recognizes human,mouse,rat antigen. The VPS4B antibody has been validated for the following applications: ELISA, WB analysis.
