TAX1BP3

gene product
TIP-1
This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
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119 antibodies from 24 providers.

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Invitrogen Antibodies
4 antibodies
Novus Biologicals
4 antibodies
Proteintech Group
1 antibody
antibodies-online
55 antibodies
NovoPro Bioscience Inc.
3 antibodies
Boster Biological Technology
1 antibody
Atlas Antibodies
2 antibodies
Abnova Corporation
3 antibodies
LifeSpan BioSciences, Inc.
9 antibodies
Abgent
1 antibody
Biorbyt
9 antibodies
NSJ Bioreagents
2 antibodies
Creative Biolabs
9 antibodies
Creative Diagnostics
2 antibodies
GeneTex
1 antibody
RabMAbs
1 antibody
St John's Laboratory
1 antibody
Abbexa
3 antibodies
MyBioSource
1 antibody
RayBiotech, Inc.
1 antibody
Leading Biology
2 antibodies
ProSci
1 antibody
Sigma-Aldrich
1 antibody
Acris Antibodies GmbH
2 antibodies