RA0508

antibody from Oursmab

Targeting: MSLN CAK1, MPF

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0508

Provider

Oursmab

Product name

Anetumab (Biosimilar Reference Antibody) (MSLN)

Antibody type

Monoclonal

Description

Anetumab is an investigational, fully human monoclonal antibody (IgG1) that targets the tumor-associated antigen mesothelin. It is developed as an antibody-drug conjugate (ADC), where the antibody is linked to the potent cytotoxic agent tubulysin B. The construct is designed to specifically deliver the toxin to mesothelin-expressing cancer cells, where it is internalized and releases the payload, leading to targeted cell death. It has been primarily investigated in clinical trials for the treatment of mesothelioma, ovarian cancer, and pancreatic cancer, representing a strategy to exploit mesothelin overexpression for targeted chemotherapy delivery.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Anetumab (Biosimilar Reference Antibody) (MSLN)-RA0508-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.