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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Flow cytometry [2]
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- Product number
- FAB32652P - Provider product page
- Provider
- R&D Systems
- Product name
- Human Mesothelin PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Mesothelin in direct ELISAs.
- Reactivity
- Human
- Host
- Rat
- Antigen sequence
AAH09272- Isotype
- IgG
- Antibody clone number
- 420411
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy.
High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients.
Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition.
An in vivo platform for tumor biomarker assessment.
Zhang E, Yang P, Gu J, Wu H, Chi X, Liu C, Wang Y, Xue J, Qi W, Sun Q, Zhang S, Hu J, Xu H
Journal of hematology & oncology 2018 Aug 13;11(1):102
Journal of hematology & oncology 2018 Aug 13;11(1):102
High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients.
Tang Y, Wang Z, Li Z, Kim J, Deng Y, Li Y, Heath JR, Wei W, Lu S, Shi Q
Proceedings of the National Academy of Sciences of the United States of America 2017 Mar 7;114(10):2544-2549
Proceedings of the National Academy of Sciences of the United States of America 2017 Mar 7;114(10):2544-2549
Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition.
Cherkassky L, Morello A, Villena-Vargas J, Feng Y, Dimitrov DS, Jones DR, Sadelain M, Adusumilli PS
The Journal of clinical investigation 2016 Aug 1;126(8):3130-44
The Journal of clinical investigation 2016 Aug 1;126(8):3130-44
An in vivo platform for tumor biomarker assessment.
Servais EL, Suzuki K, Colovos C, Rodriguez L, Sima C, Fleisher M, Rusch VW, Sadelain M, Adusumilli PS
PloS one 2011;6(10):e26722
PloS one 2011;6(10):e26722
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Mesothelin in HeLa Human Cell Line by Flow Cytometry. HeLa human cervical epithelial carcinoma cell line was stained with Rat Anti-Human Mesothelin PE-conjugated Monoclonal Antibody (Catalog # FAB32652P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Mesothelin Specificity is Shown by Flow Cytometry in Knockout Cell Line. Mesothelin knockout HeLa human cervical epithelial carcinoma cell line was stained with Rat Anti-Human Mesothelin PE-conjugated Monoclonal Antibody (Catalog # FAB32652P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). No staining in the Mesothelin knockout HeLa cell line was observed. View our protocol for Staining Membrane-associated Proteins.
