PAB13281

antibody from Abnova Corporation

Targeting: FYB1 ADAP, FYB, FYB-120/130, SLAP-130

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB13281

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB13281, RRID:AB_10549465

Product name

FYB polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of FYB.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Adhesion and degranulation-promoting adapter protein (ADAP) positively regulates T cell sensitivity to antigen and T cell survival.

Mueller KL, Thomas MS, Burbach BJ, Peterson EJ, Shimizu Y
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):3559-69

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Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1.

Medeiros RB, Burbach BJ, Mueller KL, Srivastava R, Moon JJ, Highfill S, Peterson EJ, Shimizu Y
Science (New York, N.Y.) 2007 May 4;316(5825):754-8

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Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap.

Griffiths EK, Krawczyk C, Kong YY, Raab M, Hyduk SJ, Bouchard D, Chan VS, Kozieradzki I, Oliveira-Dos-Santos AJ, Wakeham A, Ohashi PS, Cybulsky MI, Rudd CE, Penninger JM
Science (New York, N.Y.) 2001 Sep 21;293(5538):2260-3

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of FYB in K-562 cell lysate with FYB polyclonal antibody (Cat # PAB13281) at (A) 0.5 and (B) 1 ug/mL .

Immunocytochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunocytochemistry of FYB in K-562 cells with FYB polyclonal antibody (Cat # PAB13281) at 10 ug/mL .

Validation comment

Immunocytochemistry