322302

antibody from BioLegend
Targeting: KLRG1 2F1, CLEC15A, MAFA, MAFA-L
Provider product page for 322302

Antibody data

Product number
322302 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#322302, RRID:AB_535988
Product name
Purified anti-human CD57
Antibody type
Monoclonal
Antigen
CD57
Description
CD57, also known as HNK-1, NK-1, and Leu-7, is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgM
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
KLRG1 protein structure - 322302 shown in red.