BS7881

antibody from Bioworld Technology, Inc
Targeting: FIS1 CGI-135, H_NH0132A01.6, TTC11
Provider product page for BS7881
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7881 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FIS1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human FIS1.
Description
Fis1 localizes to the outer mitochondrial membrane and, along with dynamin-related protein (Drp1), participates in mitochondrial fission. Fission and fusion mechanisms regulate mitochondrial morphology within the cell. Fission frequency is determined by the level of Fis1 molecules at the mitochondrial surface. Fis1 contains a C-terminal domain, which is required for mitochondrial localization, and an N-terminal domain, which is necessary for mitochondrial fission. Fragmentation of the mitochondrial network by Fis1 leads to cytochrome c release and apoptosis. The mitochondrial fission mechanisms may be involved in positively and negatively regulating apoptosis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FIS1 protein structure - BS7881 shown in red.