66635-1-Ig

antibody from Proteintech Group

Targeting: FIS1 CGI-135, H_NH0132A01.6, TTC11

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66635-1-Ig

Provider

Proteintech Group

Product name

FIS1 antibody

Antibody type

Monoclonal

Description

FIS1 antibody (Cat. #66635-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2F10E1

Vial size

20ul, 150ul

References

Submitted references

SENP3/FIS1-regulated PFC neural mitochondrial fragmentation underlies the mechanism of electroacupuncture attenuating depressive behavior in CUMS mice.

Lai S, Qiu X, Lin P, Wu J, Li F, Lai N, Li X, Tu T, Zhang J, Huang Y, Zhang Z
Frontiers in psychiatry 2025;16:1645757

---

HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF-κB/SOD2 Signaling Pathway.

Li H, Cai S, Mu H, Chang T, Wang X, Tang T, Dong T, Zhang Y, Zhang L, Li H, Zhou L, Xiang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03828

---

CUMS stress facilitates hippocampal neural mitophagy through FIS1/MFF-mediated mitochondrial fragmentation.

Qiu X, Lai S, Zhang Y, Huang S, Zhang J, Tan Y, Li H, Liu J, Huang Y, Zhang Z
Journal of neurophysiology 2025 Sep 1;134(3):952-961

---

Revitalising Aging Oocytes: Echinacoside Restores Mitochondrial Function and Cellular Homeostasis Through Targeting GJA1/SIRT1 Pathway.

Yang L, Lai X, Lin F, Shi N, Xu X, Wang H, Li X, Shen D, Qian H, Jin X, Chen J, Huang Z, Duan X, Zhang Q
Cell proliferation 2025 Oct;58(10):e70044

---

DMT1 Maintains Iron Homeostasis to Regulate Mitochondrial Function in Porcine Oocytes.

Zhang JX, Lan MF, Shang JZ, Lai XL, Li LS, Duan TT, Xu RH, Chen KL, Duan X
Journal of cellular physiology 2025 Jan;240(1):e31494

---

HIV-1 gp120 Interactions with Nicotine Modulate Mitochondrial Network Properties and Amyloid Release in Microglia.

Graur A, Erickson N, Sinclair P, Nusir A, Kabbani N
Neurochemical research 2025 Feb 24;50(2):103

---

Harmine derivative H-2-168 induces the death of Echinococcus granulosus by regulating mitochondrial fusion and fission.

Gong Y, Zhao M, Pan M, Zhao Y, Liu J, Wen H, Wang J
Pharmaceutical biology 2025 Dec;63(1):188-200

---

Ketogenic diet ameliorates MASLD via balancing mitochondrial dynamics and improving mitochondrial dysfunction.

You Y, Ni H, Ma Q, Jiang L, Cai J, He W, Lin X, Li K, Wang Z, Yan W, Xiao X, Ma L
Nutrition & diabetes 2025 Aug 25;15(1):37

---

2-aminoethoxydiphenylborane intervenes intracellular calcium signaling and attenuates myocardial ischemia-reperfusion injury in mice through ITPR1/MCU pathway.

Bao H, Chen X, Hu X, Cao Z, Zhou W, Chen B, Liao F, Wei F, Huang R, Li W, Chen Z
Scientific reports 2025 Aug 12;15(1):29469

---

Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein.

Hu F, Tong S, Xu H
The Journal of membrane biology 2025 Apr;258(2):123-133

---

Overproduction of Mitochondrial Fission Proteins and Mitochondrial Fission in Podocytes of Lupus Nephritis Patients.

Wei Q, Wu X, Chen Z, Lin H, Xiong L, Wang N
Journal of inflammation research 2024;17:10807-10818

---

Stearic acid alleviates aortic medial degeneration through maintaining mitochondrial dynamics homeostasis via inhibiting JNK/MAPK signaling.

Wang K, Xie X, Hu X, Wang Z, Xia J, Wu Q
iScience 2024 Sep 20;27(9):110594

---

Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling.

Kalarikkal M, Saikia R, Oliveira L, Bhorkar Y, Lonare A, Varshney P, Dhamale P, Majumdar A, Joseph J
EMBO reports 2024 Oct;25(10):4226-4251

---

Procyanidin C1 ameliorates acidic pH stress induced nucleus pulposus degeneration through SIRT3/FOXO3-mediated mitochondrial dynamics.

Hua W, Xie L, Dong C, Yang G, Chi S, Xu Z, Yang C, Wang H, Wu X
Journal of translational medicine 2024 Nov 27;22(1):1071

---

Acetylated tau exacerbates apoptosis by disturbing mitochondrial dynamics in HEK293 cells.

Zhang JF, Fang ZT, Zhao JN, Liu GP, Shen X, Jiang GF, Liu Q
Journal of neurochemistry 2024 Mar;168(3):288-302

---

Fibroblast growth factor 7 protects osteoblasts against oxidative damage through targeting mitochondria.

Liu X, Hu X, Niu C, Yang Y, Huang Z, Xie J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23524

---

Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.

Li Y, Li L, Xiong W, Duan X, Xi H
Theriogenology 2024 Jan 15;214:192-200

---

Promising anti-ovarian aging herbal formulation He's Yangchao promotes in vitro maturation of oocytes from advanced maternal age mice.

Yang L, Shang J, Wang H, Ma J, Wang L, Ma Y, Shuo J, Xu X, Cheng R, Duan X, Zhang Q
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116890

---

Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.

Liu PY, Hong KF, Liu YD, Sun ZY, Zhao TT, Li XL, Lao CC, Tan SF, Zhang HY, Zhao YH, Xie Y, Xu YH
Chinese medicine 2024 Feb 16;19(1):27

---

SENP3-FIS1 axis promotes mitophagy and cell survival under hypoxia.

Zhao A, Maple L, Jiang J, Myers KN, Jones CG, Gagg H, McGarrity-Cottrell C, Rominiyi O, Collis SJ, Wells G, Rahman M, Danson SJ, Robinson D, Smythe C, Guo C
Cell death & disease 2024 Dec 5;15(12):881

---

Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics.

Zhao M, Xie J, Zhang J, Zhao B, Zhang Y, Xue J, Zhang R, Zhang R, Wang H, Li Y, Ge W, Zhou X
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124935

---

Inhibition of mitochondrial fusion via SIRT1/PDK2/PARL axis breaks mitochondrial metabolic plasticity and sensitizes cancer cells to glucose restriction therapy.

Guo Y, Luo C, Sun Y, Guo W, Zhang R, Zhang X, Ke X, Wei L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115342

---

miR-494-5p mediates the antioxidant activity of EPA by targeting the mitochondrial elongation factor 1 gene MIEF1 in HepG2 cells.

Lin Y, Wu X, Lin L, Mei Y, Zhou J, Chen C, Li J, Wu D, Liu J, Li G
The Journal of nutritional biochemistry 2023 May;115:109279

---

Acetylated tau exacerbates learning and memory impairment by disturbing with mitochondrial homeostasis.

Liu Q, Wang X, Hu Y, Zhao JN, Huang CH, Li T, Zhang BG, He Y, Wu YQ, Zhang ZJ, Wang GP, Liu GP
Redox biology 2023 Jun;62:102697

---

Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.

Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM
Frontiers in endocrinology 2022;13:962154

---

Roles of HIF-1α/BNIP3 mediated mitophagy in mitochondrial dysfunction of letrozole-induced PCOS rats.

Wang F, Han J, Wang X, Liu Y, Zhang Z
Journal of molecular histology 2022 Oct;53(5):833-842

---

Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.

Jiang XL, Tai H, Kuang JS, Zhang JY, Cui SC, Lu YX, Qi SB, Zhang SY, Li SM, Chen JP, Meng XS
Aging 2022 Oct 27;14(20):8321-8345

---

Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.

Zhong Y, Li Z, Jin R, Yao Y, He S, Lei M, Wang X, Shi C, Gao L, Peng X
Nutrients 2022 Nov 24;14(23)

---

Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics.

Shin YY, Seo Y, Oh SJ, Ahn JS, Song MH, Kang MJ, Oh JM, Lee D, Kim YH, Sung ES, Kim HS
Journal of pineal research 2022 Jan;72(1):e12779

---

Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis.

Xu L, Wang X, Chen Y, Soong L, Chen Y, Cai J, Liang Y, Sun J
Frontiers in immunology 2021;12:638575

---

Cardioprotective responses to aerobic exercise-induced physiological hypertrophy in zebrafish heart.

Chen Z, Zhou Z, Peng X, Sun C, Yang D, Li C, Zhu R, Zhang P, Zheng L, Tang C
The journal of physiological sciences : JPS 2021 Nov 8;71(1):33

---

Ampelopsin Inhibits Breast Cancer Cell Growth through Mitochondrial Apoptosis Pathway.

Li Y, Zhou Y, Wang M, Lin X, Zhang Y, Laurent I, Zhong Y, Li J
Biological & pharmaceutical bulletin 2021 Nov 1;44(11):1738-1745