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- References [7]
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- Product number
- 11657-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11657-1-AP, RRID:AB_2127514
- Product name
- INTS9 antibody
- Antibody type
- Polyclonal
- Description
- INTS9 antibody (Cat. #11657-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CFAP20 salvages arrested RNAPII from the path of co-directional replisomes.
Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9.
Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function.
Assembly mechanism of Integrator's RNA cleavage module.
Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability.
INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.
CRISPR-Cas9 mediated genetic engineering for the purification of the endogenous integrator complex from mammalian cells.
Uruci S, Boer DEC, Chrystal PW, Lalonde M, Panagopoulos A, Yakoub G, Kirdök I, de Lint K, van der Woude M, Wendel TJ, Brussee SJ, Wondergem AP, van Overbeek NK, Schotman N, Lingeman J, Ljungman M, van Oudenaarden A, van Attikum H, Vertegaal ACO, Noordermeer SM, Wolthuis RMF, Altmeyer M, Hamperl S, Tropepe V, van den Berg J, van den Heuvel D, Luijsterburg MS
Nature 2026 Feb;650(8103):1025-1034
Nature 2026 Feb;650(8103):1025-1034
Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9.
Eaton JD, Board J, Davidson L, Estell C, West S
eLife 2024 Jul 8;13
eLife 2024 Jul 8;13
Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function.
Lin MH, Jensen MK, Elrod ND, Chu HF, Haseley M, Beam AC, Huang KL, Chiang W, Russell WK, Williams K, Pröschel C, Wagner EJ, Tong L
Molecular cell 2024 Aug 8;84(15):2900-2917.e10
Molecular cell 2024 Aug 8;84(15):2900-2917.e10
Assembly mechanism of Integrator's RNA cleavage module.
Sabath K, Qiu C, Jonas S
Molecular cell 2024 Aug 8;84(15):2882-2899.e10
Molecular cell 2024 Aug 8;84(15):2882-2899.e10
Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability.
Bhowmick R, Mehta KPM, Lerdrup M, Cortez D
Molecular cell 2023 Jul 6;83(13):2357-2366.e8
Molecular cell 2023 Jul 6;83(13):2357-2366.e8
INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.
Sabath K, Stäubli ML, Marti S, Leitner A, Moes M, Jonas S
Nature communications 2020 Jul 9;11(1):3422
Nature communications 2020 Jul 9;11(1):3422
CRISPR-Cas9 mediated genetic engineering for the purification of the endogenous integrator complex from mammalian cells.
Baillat D, Russell WK, Wagner EJ
Protein expression and purification 2016 Dec;128:101-8
Protein expression and purification 2016 Dec;128:101-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The INTS9 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human INTS9. This antibody recognizes human antigen. The INTS9 antibody has been validated for the following applications: ELISA, WB analysis.
