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- Antibody Data
- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 18325-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18325-1-AP, RRID:AB_10640673
- Product name
- PHD3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PHD3 antibody (Cat. #18325-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter.
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer.
E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression.
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
WDR5 facilitates EMT and metastasis of CCA by increasing HIF-1α accumulation in Myc-dependent and independent pathways.
Prolyl hydroxylase 3 involvement in lung cancer progression under hypoxic conditions: association with hypoxia-inducible factor-1α and pyruvate kinase M2.
Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells.
Overexpression of the HIF hydroxylase PHD3 is a favorable prognosticator for gastric cancer.
Feng S, Ding B, Dai Z, Yin H, Ding Y, Liu S, Zhang K, Lin H, Xiao Z, Shen Y
Journal of translational medicine 2024 Mar 15;22(1):280
Journal of translational medicine 2024 Mar 15;22(1):280
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
Mao Y, Zhang J, Zhou Q, He X, Zheng Z, Wei Y, Zhou K, Lin Y, Yu H, Zhang H, Zhou Y, Lin P, Wu B, Yuan Y, Zhao J, Xu W, Zhao S
Cell research 2024 Jan;34(1):13-30
Cell research 2024 Jan;34(1):13-30
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
Dong J, Che J, Wu Y, Deng Y, Jiang X, He Z, Zhang J
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer.
Wang YZ, Qian YC, Yang WJ, Ye LH, Guo GD, Lv W, Huan MX, Feng XY, Wang K, Yang Z, Gao Y, Li L, Chen YL
Asian journal of andrology 2023 Mar-Apr;25(2):152-157
Asian journal of andrology 2023 Mar-Apr;25(2):152-157
E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression.
Zhou P, Peng X, Tang S, Zhang K, Tan Z, Li D, Shen L, Peng J, Yang L
Oncogene 2023 Apr;42(16):1308-1320
Oncogene 2023 Apr;42(16):1308-1320
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
Chen T, Zhang X, Ding X, Feng J, Zhang X, Xie D, Wang X
Molecular oncology 2023 Apr;17(4):695-709
Molecular oncology 2023 Apr;17(4):695-709
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.
Zeng Z, Lei S, Wang J, Yang Y, Lan J, Tian Q, Chen T, Hao X
Bioengineered 2022 May;13(5):12193-12210
Bioengineered 2022 May;13(5):12193-12210
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
Xu H, Zhao J, Li J, Zhu Z, Cui Z, Liu R, Lu R, Yao Z, Xu Q
Cell death & disease 2022 May 20;13(5):478
Cell death & disease 2022 May 20;13(5):478
WDR5 facilitates EMT and metastasis of CCA by increasing HIF-1α accumulation in Myc-dependent and independent pathways.
Chen T, Li K, Liu Z, Liu J, Wang Y, Sun R, Li Z, Qiu B, Zhang X, Ren G, Xu Y, Zhang Z
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jun 2;29(6):2134-2150
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jun 2;29(6):2134-2150
Prolyl hydroxylase 3 involvement in lung cancer progression under hypoxic conditions: association with hypoxia-inducible factor-1α and pyruvate kinase M2.
Chu X, Xiang M, Feng L, Liu H, Zhou C
Journal of thoracic disease 2019 Sep;11(9):3941-3950
Journal of thoracic disease 2019 Sep;11(9):3941-3950
Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells.
Radhakrishnan P, Ruh N, Harnoss JM, Kiss J, Mollenhauer M, Scherr AL, Platzer LK, Schmidt T, Podar K, Opferman JT, Weitz J, Schulze-Bergkamen H, Koehler BC, Ulrich A, Schneider M
Cancer research 2016 Apr 15;76(8):2219-30
Cancer research 2016 Apr 15;76(8):2219-30
Overexpression of the HIF hydroxylase PHD3 is a favorable prognosticator for gastric cancer.
Su C, Huang K, Sun L, Yang D, Zheng H, Gao C, Tong J, Zhang Q
Medical oncology (Northwood, London, England) 2012 Dec;29(4):2710-5
Medical oncology (Northwood, London, England) 2012 Dec;29(4):2710-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HT-1080 cells were subjected to SDS PAGE followed by western blot with 18325-1-AP(EGLN3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 18325-1-AP(EGLN3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PHD3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PHD3. This antibody recognizes human antigen. The PHD3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
