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- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB14556 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB14556, RRID:AB_10550799
- Product name
- EGLN3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of EGLN3.
- Storage
- Store at 4°C. Do not freeze.
Submitted references PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis.
Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness.
Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung.
Ginouvès A, Ilc K, Macías N, Pouysségur J, Berra E
Proceedings of the National Academy of Sciences of the United States of America 2008 Mar 25;105(12):4745-50
Proceedings of the National Academy of Sciences of the United States of America 2008 Mar 25;105(12):4745-50
Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness.
Jokilehto T, Rantanen K, Luukkaa M, Heikkinen P, Grenman R, Minn H, Kronqvist P, Jaakkola PM
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Feb 15;12(4):1080-7
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Feb 15;12(4):1080-7
Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung.
Asikainen TM, Schneider BK, Waleh NS, Clyman RI, Ho WB, Flippin LA, Günzler V, White CW
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 19;102(29):10212-7
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 19;102(29):10212-7
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Detection of human and rat EGLN3 by Western Blot.Samples : A. Lysate from cells that were transiently transfected with PHD1 (Lane 1), PHD2 (Lane 2), PHD3 (Lane 3) or PHD4 (Lane 4) constructs or in vitro translated.
