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- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 12488-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12488-1-AP, RRID:AB_2199923
- Product name
- TBL2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TBL2 antibody (Cat. #12488-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transducin Beta-Like 2 is a Potential Driver Gene that Adapts to Endoplasmic Reticulum Stress to Promote Tumor Growth of Lung Adenocarcinoma.
TBL2 Associates With ATF4 mRNA Via Its WD40 Domain and Regulates Its Translation During ER Stress.
The endoplasmic reticulum-localized protein TBL2 interacts with the 60S ribosomal subunit.
TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.
Kosai K, Masuda T, Kitagawa A, Tobo T, Ono Y, Ando Y, Takahashi J, Haratake N, Kohno M, Takenaka T, Yoshizumi T, Mimori K
Annals of surgical oncology 2023 Nov;30(12):7538-7548
Annals of surgical oncology 2023 Nov;30(12):7538-7548
TBL2 Associates With ATF4 mRNA Via Its WD40 Domain and Regulates Its Translation During ER Stress.
Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A
Journal of cellular biochemistry 2016 Feb;117(2):500-9
Journal of cellular biochemistry 2016 Feb;117(2):500-9
The endoplasmic reticulum-localized protein TBL2 interacts with the 60S ribosomal subunit.
Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A
Biochemical and biophysical research communications 2015 Jul 10;462(4):383-8
Biochemical and biophysical research communications 2015 Jul 10;462(4):383-8
TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.
Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A
PloS one 2014;9(11):e112761
PloS one 2014;9(11):e112761
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 12488-1-AP(TBL2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TBL2 antibody 11640-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 12488-1-AP(TBL2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
