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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [11]
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- Product number
- AF1440 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse Nogo Receptor/NgR Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects mouse Nogo Receptor in direct ELISAs and Western blots. In these formats, approximately 10% cross-reactivity with recombinant human (rh) NgR is observed and less than 1% cross-reactivity with rhNgRH1 and rhNgRH2 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q99PI8- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Nogo receptor 1 is expressed by nearly all retinal ganglion cells.
The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor.
LOTUS overexpression accelerates neuronal plasticity after focal brain ischemia in mice.
Regulation of axonal regeneration by the level of function of the endogenous Nogo receptor antagonist LOTUS.
Cell type-specific Nogo-A gene ablation promotes axonal regeneration in the injured adult optic nerve.
Plasticity of binocularity and visual acuity are differentially limited by nogo receptor.
LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition.
Localization of an axon growth inhibitory molecule Nogo and its receptor in the spinal cord of mouse embryos.
Soluble Nogo receptor down-regulates expression of neuronal Nogo-A to enhance axonal regeneration.
Reassessment of corticospinal tract regeneration in Nogo-deficient mice.
Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength.
Solomon AM, Westbrook T, Field GD, McGee AW
PloS one 2018;13(5):e0196565
PloS one 2018;13(5):e0196565
The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor.
Kawakami Y, Kurihara Y, Saito Y, Fujita Y, Yamashita T, Takei K
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Mar 7;38(10):2589-2604
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Mar 7;38(10):2589-2604
LOTUS overexpression accelerates neuronal plasticity after focal brain ischemia in mice.
Takase H, Kurihara Y, Yokoyama TA, Kawahara N, Takei K
PloS one 2017;12(9):e0184258
PloS one 2017;12(9):e0184258
Regulation of axonal regeneration by the level of function of the endogenous Nogo receptor antagonist LOTUS.
Hirokawa T, Zou Y, Kurihara Y, Jiang Z, Sakakibara Y, Ito H, Funakoshi K, Kawahara N, Goshima Y, Strittmatter SM, Takei K
Scientific reports 2017 Sep 21;7(1):12119
Scientific reports 2017 Sep 21;7(1):12119
Cell type-specific Nogo-A gene ablation promotes axonal regeneration in the injured adult optic nerve.
Vajda F, Jordi N, Dalkara D, Joly S, Christ F, Tews B, Schwab ME, Pernet V
Cell death and differentiation 2015 Feb;22(2):323-35
Cell death and differentiation 2015 Feb;22(2):323-35
Plasticity of binocularity and visual acuity are differentially limited by nogo receptor.
Stephany CÉ, Chan LL, Parivash SN, Dorton HM, Piechowicz M, Qiu S, McGee AW
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Aug 27;34(35):11631-40
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Aug 27;34(35):11631-40
LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition.
Thomas R, Favell K, Morante-Redolat J, Pool M, Kent C, Wright M, Daignault K, Ferraro GB, Montcalm S, Durocher Y, Fournier A, Perez-Tur J, Barker PA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 May 12;30(19):6607-12
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 May 12;30(19):6607-12
Localization of an axon growth inhibitory molecule Nogo and its receptor in the spinal cord of mouse embryos.
Wang J, Wang L, Zhao H, Chan SO
Brain research 2010 Jan 8;1306:8-17
Brain research 2010 Jan 8;1306:8-17
Soluble Nogo receptor down-regulates expression of neuronal Nogo-A to enhance axonal regeneration.
Peng X, Zhou Z, Hu J, Fink DJ, Mata M
The Journal of biological chemistry 2010 Jan 22;285(4):2783-95
The Journal of biological chemistry 2010 Jan 22;285(4):2783-95
Reassessment of corticospinal tract regeneration in Nogo-deficient mice.
Lee JK, Chan AF, Luu SM, Zhu Y, Ho C, Tessier-Lavigne M, Zheng B
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Jul 8;29(27):8649-54
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Jul 8;29(27):8649-54
Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength.
Lee H, Raiker SJ, Venkatesh K, Geary R, Robak LA, Zhang Y, Yeh HH, Shrager P, Giger RJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Mar 12;28(11):2753-65
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Mar 12;28(11):2753-65
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