FNab09629

antibody from FineTest Biotech

Targeting: ZFYVE19 ANCHR, FLJ14840

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Validation data

Product number: FNab09629 - Provider product page
Provider: FineTest Biotech
Product name: ZFYVE19 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4(VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: zinc finger, FYVE domain containing 19
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ZFYVE19 protein structure - FNab09629 shown in red.