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- References [29]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 13089-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13089-1-AP, RRID:AB_2304119
- Product name
- TRX2 antibody
- Antibody type
- Polyclonal
- Description
- TRX2 antibody (Cat. #13089-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.
Mechanism of KAT2A regulation of H3K36ac in manganese-induced oxidative damage to mitochondria in the nervous system and intervention by curcumin.
FNDC5/Irisin protects neurons through Caspase3 and Bax pathways.
Tremella fuciformis polysaccharides alleviates UV-provoked skin cell damage via regulation of thioredoxin interacting protein and thioredoxin reductase 2.
Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense system.
Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21.
TRX2/Rab35 Interaction Impairs Exosome Secretion by Inducing Rab35 Degradation.
Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice.
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Compartmentally scavenging hepatic oxidants through AMPK/SIRT3-PGC1α axis improves mitochondrial biogenesis and glucose catabolism.
Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
Anthocyanins inhibit high glucose-induced renal tubular cell apoptosis caused by oxidative stress in db/db mice.
Aberrant expression of redox regulatory proteins in patients with concomitant primary Sclerosing cholangitis/inflammatory bowel disease.
Effects of Hypobaric Hypoxia on Rat Retina and Protective Response of Resveratrol to the Stress.
Effects of Ranibizumab and Aflibercept on Human Müller Cells and Photoreceptors under Stress Conditions.
Delineating the Efficacy of a Cannabis-Based Medicine at Advanced Stages of Dementia in a Murine Model.
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
G6PD protects from oxidative damage and improves healthspan in mice.
Mitochondria-targeted peptide SS-31 attenuates renal injury via an antioxidant effect in diabetic nephropathy.
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Cannabis-based medicine reduces multiple pathological processes in AβPP/PS1 mice.
Age-related changes in mitochondrial antioxidant enzyme Trx2 and TXNIP-Trx2-ASK1 signal pathways in the auditory cortex of a mimetic aging rat model: changes to Trx2 in the auditory cortex.
Alteration of thioredoxin and glutaredoxin in the progression of Alzheimer's disease.
Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice.
Protective effects of the thioredoxin and glutaredoxin systems in dopamine-induced cell death.
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens.
Wang R, Mi Y, Ni J, Wang Y, Ding L, Ran X, Sun Q, Tan SY, Koeffler HP, Feng N, Chen YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939
Mechanism of KAT2A regulation of H3K36ac in manganese-induced oxidative damage to mitochondria in the nervous system and intervention by curcumin.
Liu Y, Zeng JM, Zhao H, Ao CY, Ao LH, Ban JQ, Li J
Ecotoxicology and environmental safety 2024 Mar 15;273:116155
Ecotoxicology and environmental safety 2024 Mar 15;273:116155
FNDC5/Irisin protects neurons through Caspase3 and Bax pathways.
Zhang QX, Zhang LJ, Zhao N, Chang SH, Yang L
Cell biochemistry and function 2024 Jan;42(1):e3912
Cell biochemistry and function 2024 Jan;42(1):e3912
Tremella fuciformis polysaccharides alleviates UV-provoked skin cell damage via regulation of thioredoxin interacting protein and thioredoxin reductase 2.
Lin M, Bao C, Chen L, Geng S, Wang H, Xiao Z, Gong T, Ji C, Cheng B
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2023 Oct;22(10):2285-2296
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2023 Oct;22(10):2285-2296
Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense system.
Yoon H, Park SG, Kim HJ, Shin HR, Kim KT, Cho YD, Moon JI, Park MS, Kim WJ, Ryoo HM
Experimental & molecular medicine 2023 Jul;55(7):1531-1543
Experimental & molecular medicine 2023 Jul;55(7):1531-1543
Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21.
Prutton KM, Marentette JO, Leifheit BA, Esquer H, LaBarbera DV, Anderson CC, Maclean KN, Roede JR
Free radical biology & medicine 2022 Jun;186:32-42
Free radical biology & medicine 2022 Jun;186:32-42
TRX2/Rab35 Interaction Impairs Exosome Secretion by Inducing Rab35 Degradation.
Zhang T, Zhao L, Han L, Li Y, Hu L, Wang H, Zou F
International journal of molecular sciences 2022 Jun 12;23(12)
International journal of molecular sciences 2022 Jun 12;23(12)
Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice.
Liu S, Wen X, Huang Q, Zhu M, Lu J
Antioxidants (Basel, Switzerland) 2022 Jun 10;11(6)
Antioxidants (Basel, Switzerland) 2022 Jun 10;11(6)
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Li KY, Xiang XJ, Song L, Chen J, Luo B, Wen QX, Zhong BR, Zhou GF, Deng XJ, Ma YL, Hu LT, Chen GJ
Journal of neurochemistry 2021 May;157(4):1351-1365
Journal of neurochemistry 2021 May;157(4):1351-1365
Compartmentally scavenging hepatic oxidants through AMPK/SIRT3-PGC1α axis improves mitochondrial biogenesis and glucose catabolism.
Wu M, Zhang C, Xie M, Zhen Y, Lai B, Liu J, Qiao L, Liu S, Shi D
Free radical biology & medicine 2021 May 20;168:117-128
Free radical biology & medicine 2021 May 20;168:117-128
Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.
Zeng N, Huang YQ, Yan YM, Hu ZQ, Zhang Z, Feng JX, Guo JS, Zhu JN, Fu YH, Wang XP, Zhang MZ, Duan JZ, Zheng XL, Xu JD, Shan ZX
Molecular therapy. Nucleic acids 2021 Dec 3;26:1035-1050
Molecular therapy. Nucleic acids 2021 Dec 3;26:1035-1050
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Wu C, Yang L, Tucker D, Dong Y, Zhu L, Duan R, Liu TC, Zhang Q
Medicine and science in sports and exercise 2018 May;50(5):945-956
Medicine and science in sports and exercise 2018 May;50(5):945-956
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
Li L, Yang R, Li P, Lu H, Hao J, Li L, Tucker D, Zhang Q
Molecular neurobiology 2018 Mar;55(3):2042-2055
Molecular neurobiology 2018 Mar;55(3):2042-2055
Anthocyanins inhibit high glucose-induced renal tubular cell apoptosis caused by oxidative stress in db/db mice.
Wei J, Wu H, Zhang H, Li F, Chen S, Hou B, Shi Y, Zhao L, Duan H
International journal of molecular medicine 2018 Mar;41(3):1608-1618
International journal of molecular medicine 2018 Mar;41(3):1608-1618
Aberrant expression of redox regulatory proteins in patients with concomitant primary Sclerosing cholangitis/inflammatory bowel disease.
Petersen DR, Orlicky DJ, Roede JR, Shearn CT
Experimental and molecular pathology 2018 Aug;105(1):32-36
Experimental and molecular pathology 2018 Aug;105(1):32-36
Effects of Hypobaric Hypoxia on Rat Retina and Protective Response of Resveratrol to the Stress.
Xin X, Dang H, Zhao X, Wang H
International journal of medical sciences 2017;14(10):943-950
International journal of medical sciences 2017;14(10):943-950
Effects of Ranibizumab and Aflibercept on Human Müller Cells and Photoreceptors under Stress Conditions.
Shen W, Yau B, Lee SR, Zhu L, Yam M, Gillies MC
International journal of molecular sciences 2017 Mar 1;18(3)
International journal of molecular sciences 2017 Mar 1;18(3)
Delineating the Efficacy of a Cannabis-Based Medicine at Advanced Stages of Dementia in a Murine Model.
Aso E, Andrés-Benito P, Ferrer I
Journal of Alzheimer's disease : JAD 2016 Oct 4;54(3):903-912
Journal of Alzheimer's disease : JAD 2016 Oct 4;54(3):903-912
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Li P, Zhang D, Shen L, Dong K, Wu M, Ou Z, Shi D
Scientific reports 2016 Mar 9;6:22831
Scientific reports 2016 Mar 9;6:22831
G6PD protects from oxidative damage and improves healthspan in mice.
Nóbrega-Pereira S, Fernandez-Marcos PJ, Brioche T, Gomez-Cabrera MC, Salvador-Pascual A, Flores JM, Viña J, Serrano M
Nature communications 2016 Mar 15;7:10894
Nature communications 2016 Mar 15;7:10894
Mitochondria-targeted peptide SS-31 attenuates renal injury via an antioxidant effect in diabetic nephropathy.
Hou Y, Li S, Wu M, Wei J, Ren Y, Du C, Wu H, Han C, Duan H, Shi Y
American journal of physiology. Renal physiology 2016 Mar 15;310(6):F547-59
American journal of physiology. Renal physiology 2016 Mar 15;310(6):F547-59
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Dong K, Wu M, Liu X, Huang Y, Zhang D, Wang Y, Yan LJ, Shi D
Free radical biology & medicine 2016 Dec;101:334-347
Free radical biology & medicine 2016 Dec;101:334-347
Cannabis-based medicine reduces multiple pathological processes in AβPP/PS1 mice.
Aso E, Sánchez-Pla A, Vegas-Lozano E, Maldonado R, Ferrer I
Journal of Alzheimer's disease : JAD 2015;43(3):977-91
Journal of Alzheimer's disease : JAD 2015;43(3):977-91
Age-related changes in mitochondrial antioxidant enzyme Trx2 and TXNIP-Trx2-ASK1 signal pathways in the auditory cortex of a mimetic aging rat model: changes to Trx2 in the auditory cortex.
Sun HY, Hu YJ, Zhao XY, Zhong Y, Zeng LL, Chen XB, Yuan J, Wu J, Sun Y, Kong W, Kong WJ
The FEBS journal 2015 Jul;282(14):2758-74
The FEBS journal 2015 Jul;282(14):2758-74
Alteration of thioredoxin and glutaredoxin in the progression of Alzheimer's disease.
Arodin L, Lamparter H, Karlsson H, Nennesmo I, Björnstedt M, Schröder J, Fernandes AP
Journal of Alzheimer's disease : JAD 2014;39(4):787-97
Journal of Alzheimer's disease : JAD 2014;39(4):787-97
Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice.
Brown-Borg HM, Rakoczy S, Wonderlich JA, Armstrong V, Rojanathammanee L
Longevity & healthspan 2014;3(1):10
Longevity & healthspan 2014;3(1):10
Protective effects of the thioredoxin and glutaredoxin systems in dopamine-induced cell death.
Arodin L, Miranda-Vizuete A, Swoboda P, Fernandes AP
Free radical biology & medicine 2014 Aug;73:328-36
Free radical biology & medicine 2014 Aug;73:328-36
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Wu H, Xiao Y, Zhang S, Ji S, Wei L, Fan F, Geng J, Tian J, Sun X, Qin F, Jin C, Lin J, Yin ZY, Zhang T, Luo L, Li Y, Song S, Lin SC, Deng X, Camargo F, Avruch J, Chen L, Zhou D
Cell reports 2013 May 30;3(5):1663-77
Cell reports 2013 May 30;3(5):1663-77
TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens.
Brennan LA, Lee W, Kantorow M
PloS one 2010 Nov 4;5(11):e15421
PloS one 2010 Nov 4;5(11):e15421
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 13089-1-AP(TRX2,TXN2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TRX2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TRX2. This antibody recognizes human,mouse,rat antigen. The TRX2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
