Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 323206 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#323206, RRID:AB_755958
- Product name
- PE anti-human CD105
- Antibody type
- Monoclonal
- Antigen
- L-cells transfected with human CD105
- Description
- CD105 is also known as Endoglin. It is a type I integral membrane homodimer protein with subunits of 90 kD found on vascular endothelial cells and syncytiotrophoblasts of placenta. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on activated monocytes and tissue macrophages. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation. CD105 is a component of the TGF-β receptor system in human umbilical vein endothelial cells and binds TGF-β1 and β3 with high affinity but does not bind to TGF-β2.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke.
Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome.
Honmou O, Houkin K, Matsunaga T, Niitsu Y, Ishiai S, Onodera R, Waxman SG, Kocsis JD
Brain : a journal of neurology 2011 Jun;134(Pt 6):1790-807
Brain : a journal of neurology 2011 Jun;134(Pt 6):1790-807
Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome.
Osaka M, Honmou O, Murakami T, Nonaka T, Houkin K, Hamada H, Kocsis JD
Brain research 2010 Jul 9;1343:226-35
Brain research 2010 Jul 9;1343:226-35
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human monocytic cell line THP-1 stained with 43A3 PE
- Conjugate
- Yellow dye