MAB1097

antibody from R&D Systems

Targeting: ENG CD105, END, HHT1, ORW, ORW1

Western blot (Data presented on provider website)

Antibody Data

Product number

MAB1097

Provider

R&D Systems

Product name

Human Endoglin/CD105 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human Endoglin/CD105 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows 10-50% cross-reactivity with recombinant mouse Endoglin.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

Q5T9B9


Isotype

IgG

Antibody clone number

166709

Vial size

500 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin.

Walker DG, Lue LF, Beach TG, Tooyama I
Cells 2019 Jul 23;8(7)

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Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis.

Hawinkels LJ, Kuiper P, Wiercinska E, Verspaget HW, Liu Z, Pardali E, Sier CF, ten Dijke P
Cancer research 2010 May 15;70(10):4141-50

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Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production.

Tabata T, Kawakatsu H, Maidji E, Sakai T, Sakai K, Fang-Hoover J, Aiba M, Sheppard D, Pereira L
The American journal of pathology 2008 Apr;172(4):1127-40