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Immunoprecipitation
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 372002 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#372002, RRID:AB_2632624
- Product name
- Purified anti-human CLEC1B (CLEC2)
- Antibody type
- Monoclonal
- Description
- C-type lectin domain family 1 member B (CLEC1B, CLEC2) is a 32kD, type II transmembrane protein, highly expressed on platelets and megakaryocytes. CLEC1B is involved in platelet activation and aggregation, and mediates the capture of HIV-1 by platelets. CLEC1B contains one hem-immunoreceptor tyrosine-based activation motif (hemITAM) though which interact with Syk and PLC-g. The known ligands of CLEC1B are rhodocytin and podoplanin.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- AYP1
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human platelets were stained with purified CLEC1B (clone AYP1, filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
- Conjugate
- Unconjugated
