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Western blot
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Blocking/Neutralizing [1]
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- Product number
- MAB1210 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Growth Hormone R/GHR Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Growth Hormone R/GHR in Western blots and direct ELISAs. In Western blots, no cross-reactivity with recombinant mouse GHR or recombinant rat GHR is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
P10912- Isotype
- IgG
- Antibody clone number
- 193804
- Vial size
- 500 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Growth Hormone R/GHR Inhibition of Growth Hormone-dependent Cell Proliferation and Neutralization by Human Growth Hormone R/GHR Antibody. Recombinant Human Growth Hormone R/ GHR Fc Chimera (Catalog # 1210-GR) inhibits Recom-binant Human Growth Hormone (Catalog # 1067-GH) induced pro-liferation in the Nb2-11 rat lymphoma cell line in a dose-dependent manner (orange line). Inhibition of Recom-binant Human Growth Hormone (0.2 ng/mL) activity elicited by Recom-binant Human Growth Hormone R/ GHR Fc Chimera (10 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human Growth Hormone R/GHR Monoclonal Antibody (Catalog # MAB1210). The ND50 is typically 0.025-0.1 µg/mL.
