10-4020

antibody from ABEOMICS Inc.
Targeting: CLEC9A CD370, DNGR-1, HEEE9341, UNQ9341
Provider product page for 10-4020

Antibody data

Product number
10-4020 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-ClEC9A Antibody
Antibody type
Monoclonal
Description
CLEC9A is a C-type lectin receptor involved in the sensing and presentation of antigens derived from necrotic cells. It is expressed on the surface of the mouse and human dendritic cell subsets specialized for the uptake and processing of material from dead cells. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. It possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase and can induce proinflammatory cytokine production. CLEC9A provides targeted recruitment of the adaptive immune system during infection and can also be utilized to enhance immune responses generated by vaccines.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A partial length recombinant protei
n ( a.a 15-218) of CLEC9A was used
as the immunogen for this antibody.
Isotype
IgG
Antibody clone number
ABM23H8
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
CLEC9A protein structure - 10-4020 shown in red.