BS5920
antibody from Bioworld Technology, Inc
Targeting: SGCA
A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS5920 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Sarcoglycan Ï« polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 209-254 of Human Sarcoglycan-Ï«.
- Description
- The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated Ï«-, ÉÇ-, ÎÛ- and Ñ´-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, ÉÇ- and Ñ´-sarcoglycans are associated with ÷-sarcoglycan, a glycoprotein homologous to Ï«-sarcoglycan. Additionally, a complete deficiency in Ñ´-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of Sarcoglycan-¦Á pAb at 1:500 dilutionLane1:MCF-7 cell lysateLane2:Raw264.7 cell lysateLane3:PC12 cell lysate