BS5920

antibody from Bioworld Technology, Inc
Targeting: SGCA A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1
Provider product page for BS5920
Western blot
Immunoprecipitation

Antibody data

Product number
BS5920 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Sarcoglycan Ï« polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 209-254 of Human Sarcoglycan-Ï«.
Description
The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated Ï«-, ÉÇ-, ÎÛ- and Ñ´-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, ÉÇ- and Ñ´-sarcoglycans are associated with š÷-sarcoglycan, a glycoprotein homologous to Ï«-sarcoglycan. Additionally, a complete deficiency in Ñ´-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SGCA protein structure - BS5920 shown in red.