FAB17561P
antibody from Novus Biologicals
Targeting: CLEC7A
CD369, CLECSF12, dectin-1, hDectin-1, SCARE2
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB17561P - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal Dectin-1/CLEC7A Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse Dectin-1/CLEC7A in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Dectin-1 is observed and no cross-reactivity with recombinant mouse Dectin-2 or rhDLEC is observed.
- Reactivity
- Mouse
- Host
- Rat
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references Dok3-protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity.
Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking β-glucans.
Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells.
Loh JT, Xu S, Huo JX, Kim SS, Wang Y, Lam KP
The Journal of clinical investigation 2019 Jun 10;129(7):2717-2729
The Journal of clinical investigation 2019 Jun 10;129(7):2717-2729
Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking β-glucans.
PLOS ONE Staff.
PloS one 2015;10(3):e0119244
PloS one 2015;10(3):e0119244
Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells.
Xu S, Huo J, Gunawan M, Su IH, Lam KP
The Journal of biological chemistry 2009 Aug 14;284(33):22005-11
The Journal of biological chemistry 2009 Aug 14;284(33):22005-11
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Dectin-1/CLEC7A in Mouse Blood Monocytes by Flow Cytometry. Mouse whole blood monocytes were stained with Rat Anti-Mouse Gr-1/Ly-6G APC-conjugated Monoclonal Antibody (Catalog # FAB1037A) and either (A) Rat Anti-Mouse Dectin-1/CLEC7A PE-conjugated Monoclonal Antibody (Catalog # FAB17561P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.