FAB1859A-100
antibody from R&D Systems
Targeting: CLEC7A
CD369, CLECSF12, dectin-1, hDectin-1, SCARE2
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB1859A-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Dectin-1/CLEC7A APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Dectin-1/CLEC7A in direct ELISAs. In directs ELISAs, less than 10% cross-reactivity with recombinant human (rh) DLEC and no cross-reactivity with recombinant mouse Dectin-1 or rhDectin-2 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antigen sequence
NP_072092
- Isotype
- IgG
- Antibody clone number
- 259931
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans.
Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.
The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression.
Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization.
Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity.
Tam JM, Reedy JL, Lukason DP, Kuna SG, Acharya M, Khan NS, Negoro PE, Xu S, Ward RA, Feldman MB, Dutko RA, Jeffery JB, Sokolovska A, Wivagg CN, Lassen KG, Le Naour F, Matzaraki V, Garner EC, Xavier RJ, Kumar V, van de Veerdonk FL, Netea MG, Miranti CK, Mansour MK, Vyas JM
Journal of immunology (Baltimore, Md. : 1950) 2019 Jun 1;202(11):3256-3266
Journal of immunology (Baltimore, Md. : 1950) 2019 Jun 1;202(11):3256-3266
Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.
Gresnigt MS, Cunha C, Jaeger M, Gonçalves SM, Malireddi RKS, Ammerdorffer A, Lubbers R, Oosting M, Rasid O, Jouvion G, Fitting C, Jong DJ, Lacerda JF, Campos A Jr, Melchers WJG, Lagrou K, Maertens J, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL
Nature communications 2018 Jul 6;9(1):2636
Nature communications 2018 Jul 6;9(1):2636
The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression.
Gresnigt MS, Jaeger M, Subbarao Malireddi RK, Rasid O, Jouvion G, Fitting C, Melchers WJG, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL
Frontiers in immunology 2017;8:1777
Frontiers in immunology 2017;8:1777
Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization.
van Haren SD, Dowling DJ, Foppen W, Christensen D, Andersen P, Reed SG, Hershberg RM, Baden LR, Levy O
Journal of immunology (Baltimore, Md. : 1950) 2016 Dec 1;197(11):4413-4424
Journal of immunology (Baltimore, Md. : 1950) 2016 Dec 1;197(11):4413-4424
Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity.
Kleinnijenhuis J, Quintin J, Preijers F, Benn CS, Joosten LA, Jacobs C, van Loenhout J, Xavier RJ, Aaby P, van der Meer JW, van Crevel R, Netea MG
Journal of innate immunity 2014;6(2):152-8
Journal of innate immunity 2014;6(2):152-8
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Dectin-1/CLEC7A in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human Dectin-1/CLEC7A APC-conjugated Monoclonal Antibody (Catalog # FAB1859A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.