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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB17561P - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse Dectin-1/CLEC7A PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse Dectin-1/CLEC7A in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Dectin-1 is observed and no cross-reactivity with recombinant mouse Dectin-2 or rhDLEC is observed.
- Reactivity
- Mouse
- Host
- Rat
- Antigen sequence
Q6QLQ4- Isotype
- IgG
- Antibody clone number
- 218820
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking β-glucans.
Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells.
PLOS ONE Staff.
PloS one 2015;10(3):e0119244
PloS one 2015;10(3):e0119244
Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells.
Xu S, Huo J, Gunawan M, Su IH, Lam KP
The Journal of biological chemistry 2009 Aug 14;284(33):22005-11
The Journal of biological chemistry 2009 Aug 14;284(33):22005-11
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of Dectin-1/CLEC7A in Mouse Blood Monocytes by Flow Cytometry. Mouse whole blood monocytes were stained with Rat Anti-Mouse Gr-1/Ly-6G APC-conjugated Monoclonal Antibody (Catalog # FAB1037A) and either (A) Rat Anti-Mouse Dectin-1/CLEC7A PE-conjugated Monoclonal Antibody (Catalog # FAB17561P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
