BS3395

antibody from Bioworld Technology, Inc
Targeting: PPP2R3B PPP2R3L, PPP2R3LY, PR48, PR70
Provider product page for BS3395

Antibody data

Product number
BS3395 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3395, RRID:AB_1662257
Product name
PR48 (E394) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 370-412 of Human PR48.
Description
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions. The protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. PR48 is a 48 kDa regulatory subunit of protein phosphatase 2A (PP2A). PP2A activity is required for the initiation of DNA replication in yeast, viral, and vertebrate systems. PR48 localizes to the nucleus and binds specifically to Cdc6, a highly conserved protein which is required for the formation of prereplicative complexes. PR48 is considered to be involved in the dephosphorylation of Cdc6 by PP2A, a process important to the control of DNA replication in mammalian cell.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PPP2R3B protein structure - BS3395 shown in red.