Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14270-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14270-1-AP, RRID:AB_2129841
- Product name
- ITPKA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ITPKA antibody (Cat. #14270-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A metabolism-related gene signature for predicting the prognosis in thyroid carcinoma.
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca(2+) Signaling Pathway.
Sex-specific Regulation of Spine Density and Synaptic Proteins by G-protein-coupled Estrogen Receptor (GPER)1 in Developing Hippocampus.
Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7.
Single-cell transcriptomes reveal molecular specializations of neuronal cell types in the developing cerebellum.
Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.
The catalytic domain of inositol-1,4,5-trisphosphate 3-kinase-a contributes to ITPKA-induced modulation of F-actin.
ITPKA expression is a novel prognostic factor in hepatocellular carcinoma.
Functional role of inositol-1,4,5-trisphosphate-3-kinase-A for motility of malignant transformed cells.
Du Q, Zhou R, Wang H, Li Q, Yan Q, Dang W, Guo J
Frontiers in genetics 2022;13:972950
Frontiers in genetics 2022;13:972950
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca(2+) Signaling Pathway.
Liu J, Zhang C, Wang J, Huang Y, Shen D, Hu Y, Chu H, Yu X, Zhang L, Ma H
Pharmaceuticals (Basel, Switzerland) 2022 Nov 28;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 28;15(12)
Sex-specific Regulation of Spine Density and Synaptic Proteins by G-protein-coupled Estrogen Receptor (GPER)1 in Developing Hippocampus.
Li X, Johann S, Rune GM, Bender RA
Neuroscience 2021 Sep 15;472:35-50
Neuroscience 2021 Sep 15;472:35-50
Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7.
Stoyas CA, Bushart DD, Switonski PM, Ward JM, Alaghatta A, Tang MB, Niu C, Wadhwa M, Huang H, Savchenko A, Gariani K, Xie F, Delaney JR, Gaasterland T, Auwerx J, Shakkottai VG, La Spada AR
Neuron 2020 Feb 19;105(4):630-644.e9
Neuron 2020 Feb 19;105(4):630-644.e9
Single-cell transcriptomes reveal molecular specializations of neuronal cell types in the developing cerebellum.
Peng J, Sheng AL, Xiao Q, Shen L, Ju XC, Zhang M, He ST, Wu C, Luo ZG
Journal of molecular cell biology 2019 Aug 19;11(8):636-648
Journal of molecular cell biology 2019 Aug 19;11(8):636-648
Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.
Liu M, Zhang J, Liu C
Experimental and therapeutic medicine 2018 Jan;15(1):539-547
Experimental and therapeutic medicine 2018 Jan;15(1):539-547
The catalytic domain of inositol-1,4,5-trisphosphate 3-kinase-a contributes to ITPKA-induced modulation of F-actin.
Ashour DJ, Pelka B, Jaaks P, Wundenberg T, Blechner C, Zobiak B, Failla AV, Windhorst S
Cytoskeleton (Hoboken, N.J.) 2015 Feb;72(2):93-100
Cytoskeleton (Hoboken, N.J.) 2015 Feb;72(2):93-100
ITPKA expression is a novel prognostic factor in hepatocellular carcinoma.
Li J, Zhu YH, Huang P, Zhang B, Sun J, Guan XY
Diagnostic pathology 2015 Aug 7;10:136
Diagnostic pathology 2015 Aug 7;10:136
Functional role of inositol-1,4,5-trisphosphate-3-kinase-A for motility of malignant transformed cells.
Windhorst S, Kalinina T, Schmid K, Blechner C, Kriebitzsch N, Hinsch R, Chang L, Herich L, Schumacher U, Mayr GW
International journal of cancer 2011 Sep 15;129(6):1300-9
International journal of cancer 2011 Sep 15;129(6):1300-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 14270-1-AP(ITPKA antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ITPKA antibody 14270-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 14270-1-AP(ITPKA antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 14270-1-AP(ITPKA antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue