Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations [0]
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- Product number
- MAB138-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human NKG2C/CD159c Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry. It does not cross-react with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 134591
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Cytomegalovirus-Driven Adaption of Natural Killer Cells in NKG2Cnull Human Immunodeficiency Virus-Infected Individuals.
Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells.
Severe Symptomatic Primary Human Cytomegalovirus Infection despite Effective Innate and Adaptive Immune Responses.
Ascorbic acid promotes proliferation of natural killer cell populations in culture systems applicable for natural killer cell therapy.
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
MicroRNA editing facilitates immune elimination of HCMV infected cells.
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells.
Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease.
CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets.
Fully functional NK cells after unrelated cord blood transplantation.
A novel subset of NK cells expressing high levels of inhibitory FcgammaRIIB modulating antibody-dependent function.
Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion.
Comeau EM, Holder KA, Fudge NJ, Grant MD
Viruses 2019 Mar 9;11(3)
Viruses 2019 Mar 9;11(3)
Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells.
Martrus G, Kautz T, Lunemann S, Richert L, Glau L, Salzberger W, Goebels H, Langeneckert A, Hess L, Poch T, Schramm C, Oldhafer KJ, Koch M, Tolosa E, Nashan B, Altfeld M
PloS one 2017;12(8):e0182532
PloS one 2017;12(8):e0182532
Severe Symptomatic Primary Human Cytomegalovirus Infection despite Effective Innate and Adaptive Immune Responses.
Riou R, Bressollette-Bodin C, Boutoille D, Gagne K, Rodallec A, Lefebvre M, Raffi F, Senitzer D, Imbert-Marcille BM, Retière C
Journal of virology 2017 Mar 1;91(5)
Journal of virology 2017 Mar 1;91(5)
Ascorbic acid promotes proliferation of natural killer cell populations in culture systems applicable for natural killer cell therapy.
Huijskens MJ, Walczak M, Sarkar S, Atrafi F, Senden-Gijsbers BL, Tilanus MG, Bos GM, Wieten L, Germeraad WT
Cytotherapy 2015 May;17(5):613-20
Cytotherapy 2015 May;17(5):613-20
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson MA, Kekäläinen E, Johansson H, Mjösberg J, Westgren M, Lankisch TO, Wedemeyer H, Ellis EC, Ljunggren HG, Michaëlsson J, Björkström NK
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2467-71
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2467-71
MicroRNA editing facilitates immune elimination of HCMV infected cells.
Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le VT, Galun E, Horejsi V, Isakov O, Shomron N, Wolf DG, Hengel H, Mandelboim O
PLoS pathogens 2014 Feb;10(2):e1003963
PLoS pathogens 2014 Feb;10(2):e1003963
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Charoudeh HN, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M
European journal of immunology 2013 Feb;43(2):480-7
European journal of immunology 2013 Feb;43(2):480-7
Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells.
Saghafian-Hedengren S, Sohlberg E, Theorell J, Carvalho-Queiroz C, Nagy N, Persson JO, Nilsson C, Bryceson YT, Sverremark-Ekström E
Journal of virology 2013 Dec;87(24):13446-55
Journal of virology 2013 Dec;87(24):13446-55
Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbé C, Caillat-Zucman S
PLoS pathogens 2012 Jan;8(1):e1002486
PLoS pathogens 2012 Jan;8(1):e1002486
NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease.
Angelini DF, Zambello R, Galandrini R, Diamantini A, Placido R, Micucci F, Poccia F, Semenzato G, Borsellino G, Santoni A, Battistini L
Journal of leukocyte biology 2011 Jan;89(1):75-84
Journal of leukocyte biology 2011 Jan;89(1):75-84
CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets.
Yu J, Mao HC, Wei M, Hughes T, Zhang J, Park IK, Liu S, McClory S, Marcucci G, Trotta R, Caligiuri MA
Blood 2010 Jan 14;115(2):274-81
Blood 2010 Jan 14;115(2):274-81
Fully functional NK cells after unrelated cord blood transplantation.
Beziat V, Nguyen S, Lapusan S, Hervier B, Dhedin N, Bories D, Uzunov M, Boudifa A, Trebeden-Negre H, Norol F, Marjanovic Z, Marie JP, Vernant JP, Debre P, Rio B, Vieillard V
Leukemia 2009 Apr;23(4):721-8
Leukemia 2009 Apr;23(4):721-8
A novel subset of NK cells expressing high levels of inhibitory FcgammaRIIB modulating antibody-dependent function.
Dutertre CA, Bonnin-Gélizé E, Pulford K, Bourel D, Fridman WH, Teillaud JL
Journal of leukocyte biology 2008 Dec;84(6):1511-20
Journal of leukocyte biology 2008 Dec;84(6):1511-20
Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion.
de Matos CT, Berg L, Michaëlsson J, Felländer-Tsai L, Kärre K, Söderström K
Immunology 2007 Oct;122(2):291-301
Immunology 2007 Oct;122(2):291-301
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