Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB138C-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human NKG2C/CD159c PerCP-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry. It does not cross-react with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 134591
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references CD56bright NK IL-7Rα expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections.
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
An NK Cell Population Lacking FcRγ Is Expanded in Chronically Infected HIV Patients.
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Judge CJ, Kostadinova L, Sherman KE, Butt AA, Falck-Ytter Y, Funderburg NT, Landay AL, Lederman MM, Sieg SF, Sandberg JK, Anthony DD
Journal of leukocyte biology 2017 Jul;102(1):171-184
Journal of leukocyte biology 2017 Jul;102(1):171-184
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
Gill US, Peppa D, Micco L, Singh HD, Carey I, Foster GR, Maini MK, Kennedy PT
PLoS pathogens 2016 Aug;12(8):e1005788
PLoS pathogens 2016 Aug;12(8):e1005788
An NK Cell Population Lacking FcRγ Is Expanded in Chronically Infected HIV Patients.
Zhou J, Amran FS, Kramski M, Angelovich TA, Elliott J, Hearps AC, Price P, Jaworowski A
Journal of immunology (Baltimore, Md. : 1950) 2015 May 15;194(10):4688-97
Journal of immunology (Baltimore, Md. : 1950) 2015 May 15;194(10):4688-97
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Charoudeh HN, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M
European journal of immunology 2013 Feb;43(2):480-7
European journal of immunology 2013 Feb;43(2):480-7
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of NKG2C/CD159c in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A) and either (A) Mouse Anti-Human NKG2C/CD159c PerCP-conjugated Monoclonal Antibody (Catalog # FAB138C) or (B) Mouse IgG1 PerCP Isotype Control (Catalog # IC002C). View our protocol for Staining Membrane-associated Proteins.