Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 14925-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14925-1-AP, RRID:AB_2081682
- Product name
- CNDP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CNDP2 antibody (Cat. #14925-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exercise-induced Metabolite N-lactoyl-phenylalanine Ameliorates Colitis by Inhibiting M1 Macrophage Polarization via the Suppression of the NF-κB Signaling Pathway.
Carnosine alleviates oxidative stress to prevent cellular senescence by regulating Nrf2/HO-1 pathway: a promising anti-aging strategy for oral mucosa.
Exercise-induced lactate suppresses ccRCC via CNDP2-mediated depletion of intracellular amino acids.
Endogenous histidine peptides are physiological antioxidants that prevent oligodendrocyte cell death and myelin loss in vivo.
A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites.
Cooperative nutrient scavenging is an evolutionary advantage in cancer.
Transcriptome- and proteome-wide effects of a circular RNA encompassing four early exons of the spinal muscular atrophy genes.
Transcriptome- and proteome-wide effects of a circular RNA encompassing four early exons of the spinal muscular atrophy genes.
Lac-Phe mediates the effects of metformin on food intake and body weight.
Knock-out of dipeptidase CN2 in human proximal tubular cells disrupts dipeptide and amino acid homeostasis and para- and transcellular solute transport.
Lac-Phe mediates the anti-obesity effect of metformin.
The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study.
Immune microenvironment infiltration landscape and immune-related subtypes in prostate cancer.
The proteome of granulovacuolar degeneration and neurofibrillary tangles in Alzheimer's disease.
CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications.
Family-wide Annotation of Enzymatic Pathways by Parallel In Vivo Metabolomics.
Quantitative proteomics approach to screening of potential diagnostic and therapeutic targets for laryngeal carcinoma.
Up-regulation of CNDP2 facilitates the proliferation of colon cancer.
Underexpressed CNDP2 participates in gastric cancer growth inhibition through activating the MAPK signaling pathway.
Yu R, Zhang C, Yuan M, Ye S, Hu T, Chen S, Liang G, Liu J, Ke H, Huang J, Lan P, He X, Wu X
Cellular and molecular gastroenterology and hepatology 2025;19(10):101558
Cellular and molecular gastroenterology and hepatology 2025;19(10):101558
Carnosine alleviates oxidative stress to prevent cellular senescence by regulating Nrf2/HO-1 pathway: a promising anti-aging strategy for oral mucosa.
He H, Lv C, Xie Y, Li W, Ling Z, Cheng B, Tao X
Frontiers in pharmacology 2025;16:1559584
Frontiers in pharmacology 2025;16:1559584
Exercise-induced lactate suppresses ccRCC via CNDP2-mediated depletion of intracellular amino acids.
Miao R, Liu C, Wang Y, Li H, Han C, Wang C, Tian Z, Liu J
Cell death discovery 2025 Jul 31;11(1):356
Cell death discovery 2025 Jul 31;11(1):356
Endogenous histidine peptides are physiological antioxidants that prevent oligodendrocyte cell death and myelin loss in vivo.
Sajrawi C, Odeh M, Tiwari AK, Agranovich B, Abramovich I, Zubedat S, Saar G, Shaulov L, Avital A, Reznik D, Benhar M, Radzishevsky I, Engelender S, Wolosker H
Glia 2025 Jan;73(1):122-139
Glia 2025 Jan;73(1):122-139
A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites.
Moya-Garzon MD, Wang M, Li VL, Lyu X, Wei W, Tung AS, Raun SH, Zhao M, Coassolo L, Islam H, Oliveira B, Dai Y, Spaas J, Delgado-Gonzalez A, Donoso K, Alvarez-Buylla A, Franco-Montalban F, Letian A, Ward CP, Liu L, Svensson KJ, Goldberg EL, Gardner CD, Little JP, Banik SM, Xu Y, Long JZ
Cell 2025 Jan 9;188(1):175-186.e20
Cell 2025 Jan 9;188(1):175-186.e20
Cooperative nutrient scavenging is an evolutionary advantage in cancer.
Guzelsoy G, Elorza SD, Ros M, Schachtner LT, Hayashi M, Hobson-Gutierrez S, Rundstrom P, Brunner JS, Pillai R, Walkowicz WE, Finley LWS, Deforet M, Papagiannakopoulos T, Carmona-Fontaine C
Nature 2025 Apr;640(8058):534-542
Nature 2025 Apr;640(8058):534-542
Transcriptome- and proteome-wide effects of a circular RNA encompassing four early exons of the spinal muscular atrophy genes.
Luo D, Ottesen EW, Lee JH, Singh RN
Scientific reports 2024 May 7;14(1):10442
Scientific reports 2024 May 7;14(1):10442
Transcriptome- and proteome-wide effects of a circular RNA encompassing four early exons of the spinal muscular atrophy genes.
Luo D, Ottesen E, Lee JH, Singh R
Research square 2024 Feb 28;
Research square 2024 Feb 28;
Lac-Phe mediates the effects of metformin on food intake and body weight.
Xiao S, Li VL, Lyu X, Chen X, Wei W, Abbasi F, Knowles JW, Tung AS, Deng S, Tiwari G, Shi X, Zheng S, Farrell L, Chen ZZ, Taylor KD, Guo X, Goodarzi MO, Wood AC, Chen YI, Lange LA, Rich SS, Rotter JI, Clish CB, Tahir UA, Gerszten RE, Benson MD, Long JZ
Nature metabolism 2024 Apr;6(4):659-669
Nature metabolism 2024 Apr;6(4):659-669
Knock-out of dipeptidase CN2 in human proximal tubular cells disrupts dipeptide and amino acid homeostasis and para- and transcellular solute transport.
Pfeffer T, Krug SM, Kracke T, Schürfeld R, Colbatzky F, Kirschner P, Medert R, Freichel M, Schumacher D, Bartosova M, Zarogiannis SG, Muckenthaler MU, Altamura S, Pezer S, Volk N, Schwab C, Duensing S, Fleming T, Heidenreich E, Zschocke J, Hell R, Poschet G, Schmitt CP, Peters V
Acta physiologica (Oxford, England) 2024 Apr;240(4):e14126
Acta physiologica (Oxford, England) 2024 Apr;240(4):e14126
Lac-Phe mediates the anti-obesity effect of metformin.
Xiao S, Li VL, Lyu X, Chen X, Wei W, Abbasi F, Knowles JW, Deng S, Tiwari G, Shi X, Zheng S, Farrell L, Chen ZZ, Taylor KD, Guo X, Goodarzi MO, Wood AC, Ida Chen YD, Lange LA, Rich SS, Rotter JI, Clish CB, Tahir UA, Gerszten RE, Benson MD, Long JZ
bioRxiv : the preprint server for biology 2023 Nov 4;
bioRxiv : the preprint server for biology 2023 Nov 4;
The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study.
E Y, Yu Q, Sun T, Xue H, Zhao XR, Zheng HC
BMC cancer 2023 Jun 8;23(1):520
BMC cancer 2023 Jun 8;23(1):520
Immune microenvironment infiltration landscape and immune-related subtypes in prostate cancer.
Wu W, Wang X, Le W, Lu C, Li H, Zhu Y, Chen X, An W, Xu C, Wu Q, Wang L
Frontiers in immunology 2022;13:1001297
Frontiers in immunology 2022;13:1001297
The proteome of granulovacuolar degeneration and neurofibrillary tangles in Alzheimer's disease.
Hondius DC, Koopmans F, Leistner C, Pita-Illobre D, Peferoen-Baert RM, Marbus F, Paliukhovich I, Li KW, Rozemuller AJM, Hoozemans JJM, Smit AB
Acta neuropathologica 2021 Mar;141(3):341-358
Acta neuropathologica 2021 Mar;141(3):341-358
CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications.
Schmöhl F, Peters V, Schmitt CP, Poschet G, Büttner M, Li X, Weigand T, Poth T, Volk N, Morgenstern J, Fleming T, Nawroth PP, Kroll J
Cellular and molecular life sciences : CMLS 2019 Nov;76(22):4551-4568
Cellular and molecular life sciences : CMLS 2019 Nov;76(22):4551-4568
Family-wide Annotation of Enzymatic Pathways by Parallel In Vivo Metabolomics.
Kim JT, Li VL, Terrell SM, Fischer CR, Long JZ
Cell chemical biology 2019 Nov 21;26(11):1623-1629.e3
Cell chemical biology 2019 Nov 21;26(11):1623-1629.e3
Quantitative proteomics approach to screening of potential diagnostic and therapeutic targets for laryngeal carcinoma.
Li L, Zhang Z, Wang C, Miao L, Zhang J, Wang J, Jiao B, Zhao S
PloS one 2014;9(2):e90181
PloS one 2014;9(2):e90181
Up-regulation of CNDP2 facilitates the proliferation of colon cancer.
Xue C, Zhang Z, Yu H, Yu M, Yuan K, Yang T, Miao M, Shi H
BMC gastroenterology 2014 May 21;14:96
BMC gastroenterology 2014 May 21;14:96
Underexpressed CNDP2 participates in gastric cancer growth inhibition through activating the MAPK signaling pathway.
Zhang Z, Miao L, Xin X, Zhang J, Yang S, Miao M, Kong X, Jiao B
Molecular medicine (Cambridge, Mass.) 2014 Mar 13;20(1):17-28
Molecular medicine (Cambridge, Mass.) 2014 Mar 13;20(1):17-28
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The CNDP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CNDP2. This antibody recognizes human, mouse, rat antigen. The CNDP2 antibody has been validated for the following applications: ELISA, WB analysis.