Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10924-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10924-2-AP, RRID:AB_2238881
- Product name
- SCNN1A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SCNN1A antibody (Cat. #10924-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Jiawei Shoutai Pill promotes decidualization by regulating the SGK1/ENaC pathway in recurrent spontaneous abortion.
Renal Natriuretic Peptide Receptor-C Deficiency Attenuates NaCl Cotransporter Activity in Angiotensin II-Induced Hypertension.
MLL4 mediates differentiation and tumor suppression through ferroptosis.
miR‑95 promotes osteosarcoma growth by targeting SCNN1A.
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Estradiol promotes trophoblast viability and invasion by activating SGK1.
Ursodeoxycholic acid stimulates alveolar fluid clearance in LPS-induced pulmonary edema via ALX/cAMP/PI3K pathway.
Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.
Hybrid Lipid/Polymer Nanoparticles for Pulmonary Delivery of siRNA: Development and Fate Upon In Vitro Deposition on the Human Epithelial Airway Barrier.
Oxymatrine attenuates lipopolysaccharide-induced acute lung injury by activating the epithelial sodium channel and suppressing the JNK signaling pathway.
SPX-101 Is a Novel Epithelial Sodium Channel-targeted Therapeutic for Cystic Fibrosis That Restores Mucus Transport.
ENaC mediates human extravillous trophblast cell line (HTR8/SVneo) invasion by regulating levels of matrix metalloproteinase 2 (MMP2).
Increased cystic fibrosis transmembrane conductance regulators expression and decreased epithelial sodium channel alpha subunits expression in early abortion: findings from a mouse model and clinical cases of abortion.
Reduced expression of Enac in Placenta tissues of patients with severe preeclampsia is related to compromised trophoblastic cell migration and invasion during pregnancy.
Dysregulation of the epigenome in triple-negative breast cancers: basal-like and claudin-low breast cancers express aberrant DNA hypermethylation.
Di X, Duan Z, Ma Y, Song X, Hao Y, Li G, Tan Z, Lou Y, Lin X
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116939
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116939
Renal Natriuretic Peptide Receptor-C Deficiency Attenuates NaCl Cotransporter Activity in Angiotensin II-Induced Hypertension.
Shao S, Li XD, Lu YY, Li SJ, Chen XH, Zhou HD, He S, Guo YT, Lu X, Gao PJ, Wang JG
Hypertension (Dallas, Tex. : 1979) 2021 Mar 3;77(3):868-881
Hypertension (Dallas, Tex. : 1979) 2021 Mar 3;77(3):868-881
MLL4 mediates differentiation and tumor suppression through ferroptosis.
Egolf S, Zou J, Anderson A, Simpson CL, Aubert Y, Prouty S, Ge K, Seykora JT, Capell BC
Science advances 2021 Dec 10;7(50):eabj9141
Science advances 2021 Dec 10;7(50):eabj9141
miR‑95 promotes osteosarcoma growth by targeting SCNN1A.
Geng Y, Zhao S, Jia Y, Xia G, Li H, Fang Z, Zhang Q, Tian R
Oncology reports 2020 May;43(5):1429-1436
Oncology reports 2020 May;43(5):1429-1436
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Tu J, Zhang B, Fang G, Chang W, Zhao Y
Experimental cell research 2020 May 15;390(2):111958
Experimental cell research 2020 May 15;390(2):111958
Estradiol promotes trophoblast viability and invasion by activating SGK1.
He WH, Jin MM, Liu AP, Zhou Y, Hu XL, Zhu YM, Liu AX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109092
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109092
Ursodeoxycholic acid stimulates alveolar fluid clearance in LPS-induced pulmonary edema via ALX/cAMP/PI3K pathway.
Niu F, Xu X, Zhang R, Sun L, Gan N, Wang A
Journal of cellular physiology 2019 Nov;234(11):20057-20065
Journal of cellular physiology 2019 Nov;234(11):20057-20065
Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.
Zhang J, Li S, Deng F, Baikeli B, Yu W, Liu G
Scientific reports 2019 Nov 12;9(1):16639
Scientific reports 2019 Nov 12;9(1):16639
Hybrid Lipid/Polymer Nanoparticles for Pulmonary Delivery of siRNA: Development and Fate Upon In Vitro Deposition on the Human Epithelial Airway Barrier.
d'Angelo I, Costabile G, Durantie E, Brocca P, Rondelli V, Russo A, Russo G, Miro A, Quaglia F, Petri-Fink A, Rothen-Rutishauser B, Ungaro F
Journal of aerosol medicine and pulmonary drug delivery 2018 Jun;31(3):170-181
Journal of aerosol medicine and pulmonary drug delivery 2018 Jun;31(3):170-181
Oxymatrine attenuates lipopolysaccharide-induced acute lung injury by activating the epithelial sodium channel and suppressing the JNK signaling pathway.
Jin B, Jin H
Experimental animals 2018 Jul 30;67(3):337-347
Experimental animals 2018 Jul 30;67(3):337-347
SPX-101 Is a Novel Epithelial Sodium Channel-targeted Therapeutic for Cystic Fibrosis That Restores Mucus Transport.
Scott DW, Walker MP, Sesma J, Wu B, Stuhlmiller TJ, Sabater JR, Abraham WM, Crowder TM, Christensen DJ, Tarran R
American journal of respiratory and critical care medicine 2017 Sep 15;196(6):734-744
American journal of respiratory and critical care medicine 2017 Sep 15;196(6):734-744
ENaC mediates human extravillous trophblast cell line (HTR8/SVneo) invasion by regulating levels of matrix metalloproteinase 2 (MMP2).
Yang Y, He G, Xu W, Liu X
Placenta 2015 May;36(5):587-93
Placenta 2015 May;36(5):587-93
Increased cystic fibrosis transmembrane conductance regulators expression and decreased epithelial sodium channel alpha subunits expression in early abortion: findings from a mouse model and clinical cases of abortion.
Zhou M, Fu J, Huang W, Shen L, Xiao L, Song Y, Liu Y
PloS one 2014;9(6):e99521
PloS one 2014;9(6):e99521
Reduced expression of Enac in Placenta tissues of patients with severe preeclampsia is related to compromised trophoblastic cell migration and invasion during pregnancy.
Wang S, He G, Yang Y, Liu Y, Diao R, Sheng K, Liu X, Xu W
PloS one 2013;8(8):e72153
PloS one 2013;8(8):e72153
Dysregulation of the epigenome in triple-negative breast cancers: basal-like and claudin-low breast cancers express aberrant DNA hypermethylation.
Roll JD, Rivenbark AG, Sandhu R, Parker JS, Jones WD, Carey LA, Livasy CA, Coleman WB
Experimental and molecular pathology 2013 Dec;95(3):276-87
Experimental and molecular pathology 2013 Dec;95(3):276-87
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The SCNN1A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SCNN1A. This antibody recognizes human,mouse,rat antigen. The SCNN1A antibody has been validated for the following applications: ELISA, WB analysis.