orb154035

antibody from Biorbyt

Targeting: MAPKBP1 KIAA0596, NPHP20

Western blot (Data presented on provider website)

Antibody Data

Product number

orb154035

Provider

Biorbyt

Product name

MAPKBP1 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody to MAPKBP1. MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP1 (mitogenactivated protein kinase binding protein 1), also known as JNKBP1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptorassociated factor 2) and Tak1 (TGF beta activated kinase 1), MAPKBP1 is thought to act an adaptor protein for NFkB (nuclear factor kB) activation. MAPKBP1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, PraderWilli syndrome, TaySachs disease and Marfan syndrome are all associated with defects in chromosome 15localized genes.

Reactivity

Human, Mouse, Rat

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 ul

Storage

Store at -20°C. Avoid freeze / thaw cycles.