Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 16846-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- GPX8 antibody
- Antibody type
- Polyclonal
- Description
- GPX8 antibody (Cat. #16846-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Expression patterns of glutathione peroxidases family members during tooth development.
Identification and Experimental Validation of Oxidative Stress-Related Biomarkers in Ulcerative Colitis Using Machine Learning.
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Multi-omics study reveals Shuangshen Pingfei formula regulates EETs metabolic reprogramming to exert its therapeutic effect on pulmonary fibrosis.
Luminal H(2) O(2) promotes ER Ca(2+) dysregulation and toxicity of palmitate in insulin-secreting INS-1E cells.
SARS-CoV-2 nucleocapsid protein enhances the level of mitochondrial reactive oxygen species.
Glutathione peroxidase 8 expression on cancer cells and cancer-associated fibroblasts facilitates lung cancer metastasis.
Chosen Antioxidant Enzymes GPx4 and GPx8 in Human Colorectal Carcinoma: Study of the Slovak Population.
ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity.
Zhou K, Tian Q, Zheng L, Du W
Journal of molecular histology 2026 Feb 20;57(2)
Journal of molecular histology 2026 Feb 20;57(2)
Identification and Experimental Validation of Oxidative Stress-Related Biomarkers in Ulcerative Colitis Using Machine Learning.
Duan S, Yi Q, Qiu M, Zhu Z, Zhang Z, Gao Y, Zhang D
Journal of inflammation research 2025;18:11415-11435
Journal of inflammation research 2025;18:11415-11435
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Dong C, Gao Z, Li X
Journal of translational medicine 2025 Dec 2;23(1):1369
Journal of translational medicine 2025 Dec 2;23(1):1369
Multi-omics study reveals Shuangshen Pingfei formula regulates EETs metabolic reprogramming to exert its therapeutic effect on pulmonary fibrosis.
Chen Y, Liu J, Sun Y, Li M, Fan X, Gu X
International immunopharmacology 2024 Dec 25;143(Pt 1):113275
International immunopharmacology 2024 Dec 25;143(Pt 1):113275
Luminal H(2) O(2) promotes ER Ca(2+) dysregulation and toxicity of palmitate in insulin-secreting INS-1E cells.
Sharifi S, Böger M, Lortz S, Mehmeti I
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22685
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22685
SARS-CoV-2 nucleocapsid protein enhances the level of mitochondrial reactive oxygen species.
Yu H, Yang L, Han Z, Zhou X, Zhang Z, Sun T, Zheng F, Yang J, Guan F, Xie J, Liu C
Journal of medical virology 2023 Dec;95(12):e29270
Journal of medical virology 2023 Dec;95(12):e29270
Glutathione peroxidase 8 expression on cancer cells and cancer-associated fibroblasts facilitates lung cancer metastasis.
Xu YL, Yuan LW, Jiang XM, Su MX, Huang MY, Chen YC, Zhang LL, Chen X, Zhu H, Lu JJ
MedComm 2022 Sep;3(3):e152
MedComm 2022 Sep;3(3):e152
Chosen Antioxidant Enzymes GPx4 and GPx8 in Human Colorectal Carcinoma: Study of the Slovak Population.
Pavliuk-Karachevtseva A, Mihalik J, Biel R, Rybárová S, Hodorová I
Medicina (Kaunas, Lithuania) 2022 Feb 16;58(2)
Medicina (Kaunas, Lithuania) 2022 Feb 16;58(2)
ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity.
Mehmeti I, Lortz S, Avezov E, Jörns A, Lenzen S
Free radical biology & medicine 2017 Nov;112:121-130
Free radical biology & medicine 2017 Nov;112:121-130
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The GPX8 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GPX8. This antibody recognizes human,mouse,rat antigen. The GPX8 antibody has been validated for the following applications: ELISA, WB analysis.