KBTBD7

The protein encoded by this gene is a transcriptional activator, having been shown to increase the transcription of activator protein-1 and serum response element. The encoded protein can also form a complex with KBTBD6 and CUL3, which regulates the ubiquitylation and degradation of TIAM1, which is a regulator of RAC1. [provided by RefSeq, Jul 2016]

Description

Kelch repeat and BTB domain containing 7

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

13 (41189834 - 41194569)

Ensembl ID

ENSG00000120696  (ver. 103.38)

Orthologs

-

UniProt

Q8WVZ9

neXtProt

NX_Q8WVZ9

Human splice variants

Protein structure