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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 14841-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14841-1-AP, RRID:AB_2190371
- Product name
- SLC25A6-Specific antibody
- Antibody type
- Polyclonal
- Description
- SLC25A6-Specific antibody (Cat. #14841-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis.
Carvacrol Regulates the Expression of SLC25A6 by Inhibiting VDAC1 to Improve Mitochondrial Function and Reduce LPS-Induced Inflammatory Injury in HMEC-1 Cells.
Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.
MRPL13 enhances mitochondrial function and promotes tumor progression in ovarian cancer by inhibiting mPTP opening via SLC25A6.
PTPMT1 regulates mitochondrial death through the SLC25A6-NDUFS2 axis in pancreatic cancer cells.
MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
Discovery and validation of FBLN1 and ANT3 as potential biomarkers for early detection of cervical cancer.
Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos.
Mutations of the mitochondrial carrier translocase channel subunit TIM22 cause early-onset mitochondrial myopathy.
TIM29 is a subunit of the human carrier translocase required for protein transport.
Zhou H, Fu W, Liu S, Zhang Z, Luo H, Zhong Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e02239
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e02239
Carvacrol Regulates the Expression of SLC25A6 by Inhibiting VDAC1 to Improve Mitochondrial Function and Reduce LPS-Induced Inflammatory Injury in HMEC-1 Cells.
Lu C, Yang B, Liu Y, Liu W, Yan J, Guo C, Song T, Wang X
ACS omega 2025 Mar 4;10(8):8512-8522
ACS omega 2025 Mar 4;10(8):8512-8522
Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.
Nanamatsu A, Rhodes GJ, LaFavers KA, Micanovic R, Lazar V, Khan S, Barwinska D, Makino S, Zollman A, Cheng YH, Doud EH, Mosley AL, Repass MJ, Kamocka MM, Baride A, Phillips CL, Kelly KJ, Eadon MT, Himmelfarb J, Kretzler M, Bacallao RL, Dagher PC, Hato T, El-Achkar TM
The Journal of clinical investigation 2025 Jun 16;135(12)
The Journal of clinical investigation 2025 Jun 16;135(12)
MRPL13 enhances mitochondrial function and promotes tumor progression in ovarian cancer by inhibiting mPTP opening via SLC25A6.
Liu O, Hu Y, Wang S, Nie X, Wang Y, Fan X, Zeng K, Li X, Liu B, Lin B
Cell death & disease 2025 Aug 21;16(1):634
Cell death & disease 2025 Aug 21;16(1):634
PTPMT1 regulates mitochondrial death through the SLC25A6-NDUFS2 axis in pancreatic cancer cells.
Ding PP, Huang XD, Shen L, Du L, Cheng XC, Lu YX, Liu H, Lin DD, Xiao FJ
American journal of cancer research 2023;13(3):992-1003
American journal of cancer research 2023;13(3):992-1003
MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
Ji X, Chu L, Su D, Sun J, Song P, Sun S, Wang Y, Mu Q, Liu Y, Wan Q
iScience 2023 May 19;26(5):106656
iScience 2023 May 19;26(5):106656
Discovery and validation of FBLN1 and ANT3 as potential biomarkers for early detection of cervical cancer.
Hao Y, Ye M, Chen X, Zhao H, Hasim A, Guo X
Cancer cell international 2021 Feb 18;21(1):125
Cancer cell international 2021 Feb 18;21(1):125
Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos.
Gomkale R, Cruz-Zaragoza LD, Suppanz I, Guiard B, Montoya J, Callegari S, Pacheu-Grau D, Warscheid B, Rehling P
Current biology : CB 2020 Mar 23;30(6):1119-1127.e5
Current biology : CB 2020 Mar 23;30(6):1119-1127.e5
Mutations of the mitochondrial carrier translocase channel subunit TIM22 cause early-onset mitochondrial myopathy.
Pacheu-Grau D, Callegari S, Emperador S, Thompson K, Aich A, Topol SE, Spencer EG, McFarland R, Ruiz-Pesini E, Torkamani A, Taylor RW, Montoya J, Rehling P
Human molecular genetics 2018 Dec 1;27(23):4135-4144
Human molecular genetics 2018 Dec 1;27(23):4135-4144
TIM29 is a subunit of the human carrier translocase required for protein transport.
Callegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P
FEBS letters 2016 Dec;590(23):4147-4158
FEBS letters 2016 Dec;590(23):4147-4158
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 14841-1-AP(SLC25A6-Specific antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SLC25A6-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human SLC25A6-Specific. This antibody recognizes human antigen. The SLC25A6-Specific antibody has been validated for the following applications: ELISA, IHC, IF, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 14841-1-AP(SLC25A6-Specific antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 14841-1-AP(SLC25A6-Specific antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
