Antibody data

Product number
PA1-32336 - Provider product page
Provider
Invitrogen Antibodies
Product name
NTHL1 Polyclonal Antibody
Antibody type
Polyclonal
Antigen
Recombinant full-length protein
Description
Description: The monoclonal antibody 2D3 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small alternatively spliced cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with beta3 integrins CD51/CD61 and CD41/CD61. Furthermore this interaction can mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages. CD47 is the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100 µL
Concentration
Conc. Not Determined
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
NTHL1 protein structure - PA1-32336 shown in red.