RA0382

antibody from Oursmab

Targeting: IL31RA CRL, CRL3, GLM-R, Glmr, IL-31RA

Western blot (Data presented on provider website)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0382

Provider

Oursmab

Product name

Nolavetbart (Biosimilar Reference Antibody) (IL31RA (Canine))

Antibody type

Monoclonal

Description

Nolavetbart is a caninized IgG2-kappa monoclonal antibody specifically developed for veterinary use. It targets the canine interleukin-31 receptor alpha (IL-31RA), a key component of the receptor for the pruritic (itch-inducing) cytokine IL-31. As an IgG2 isotype, it is engineered to minimize effector functions (e.g., reduced risk of antibody-dependent cellular cytotoxicity) while focusing on receptor blockade. By binding to canine IL-31RA, nolavetbart prevents IL-31 from activating its receptor, thereby inhibiting the downstream signaling pathway that triggers pruritus and inflammation.

Reactivity

Canine

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg-500,10 mg,25 mg,50 mg,579 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.