PA5-57754

antibody from Invitrogen Antibodies

Targeting: UGDH

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-57754

Provider

Invitrogen Antibodies

Product name

UGDH Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant full-length protein

Description

Immunogen sequence: IDMNDYQRRR FASRIIDSLF NTVTDKKIAI LGFAFKKDTG DTRESSSIYI SKYLMDEGAH LHIYDPKVPR EQIVVDLSHP GVSEDDQVSR LV Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.1 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

UDP-glucose dehydrogenase (UGDH) activity is suppressed by peroxide and promoted by PDGF in fibroblast-like synoviocytes: Evidence of a redox control mechanism.

Chandrasekaran R, Mathieu C, Sheth R, Cheng AP, Fong D, McCormack R, El-Gabalawy H, Alishetty S, Paige M, Hoemann CD
PloS one 2022;17(9):e0274420

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

S2 Fig UGDH protein showed detectable nuclear staining in selected cells. (A-D) Phase contrast and (E-H) matching epifluorescent images of UGDH immunostain and (I-L) DAPI-counterstained fluorescent nuclei (I-L) of FLS (P4) extracted from a synovial biopsy from a 23-year old male donor and cultured under different cytokine conditions as indicated, fixed in acetone, and immunostained for UGDH with red substrate detection which is fluorescent. Symbols: small white arrows: cytosolic UGDH immunostain; open arrows: detectable nuclear UGDH immunostain. Scale bars: 20 mum. (TIF) Click here for additional data file.