Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11680-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11680-1-AP, RRID:AB_2163182
- Product name
- Profilin 1 antibody
- Antibody type
- Polyclonal
- Description
- Profilin 1 antibody (Cat. #11680-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references METTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1.
The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence.
LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis.
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
Profilin 1 Negatively Regulates Osteoclast Migration in Postnatal Skeletal Growth, Remodeling, and Homeostasis in Mice.
Upregulation and hypomethylation of lncRNA AFAP1‑AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer.
Proteomic analysis of rat serum revealed the effects of chronic sleep deprivation on metabolic, cardiovascular and nervous system.
Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.
AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
The molecular mechanism for effects of TiN coating on NiTi alloy on endothelial cell function.
Yang R, Yang C, Su D, Song Y, Min J, Qian Z, Shen X, Li J, Su H
Cancer gene therapy 2024 Apr;31(4):562-573
Cancer gene therapy 2024 Apr;31(4):562-573
The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence.
Ayoubi R, McDowell I, Fotouhi M, Southern K, McPherson PS, Laflamme C, NeuroSGC/YCharOS/EDDU collaborative group, ABIF Consortium
F1000Research 2023;12:348
F1000Research 2023;12:348
LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis.
Yu Z, Zhu M, Shu D, Zhang R, Xiang Z, Jiang A, Liu S, Zhang C, Yuan Q, Hu X
Life sciences 2023 Jan 15;313:121276
Life sciences 2023 Jan 15;313:121276
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
Chen X, Song QL, Wang JY, Ji R, Li ZH, Cao ML, Mu XF, Guo DY, Zhang Y, Yang J
The American journal of pathology 2023 Aug;193(8):1059-1071
The American journal of pathology 2023 Aug;193(8):1059-1071
Profilin 1 Negatively Regulates Osteoclast Migration in Postnatal Skeletal Growth, Remodeling, and Homeostasis in Mice.
Shirakawa J, Kajikawa S, Böttcher RT, Costell M, Izu Y, Hayata T, Noda M, Ezura Y
JBMR plus 2019 Jun;3(6):e10130
JBMR plus 2019 Jun;3(6):e10130
Upregulation and hypomethylation of lncRNA AFAP1‑AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer.
Bo H, Fan L, Gong Z, Liu Z, Shi L, Guo C, Li X, Liao Q, Zhang W, Zhou M, Xiang B, Li X, Li G, Xiong W, Zeng Z, Cao K, Zhang S, Xiong F
Oncology reports 2019 Apr;41(4):2431-2439
Oncology reports 2019 Apr;41(4):2431-2439
Proteomic analysis of rat serum revealed the effects of chronic sleep deprivation on metabolic, cardiovascular and nervous system.
Ma B, Chen J, Mu Y, Xue B, Zhao A, Wang D, Chang D, Pan Y, Liu J
PloS one 2018;13(9):e0199237
PloS one 2018;13(9):e0199237
Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.
Lian Y, Xiong F, Yang L, Bo H, Gong Z, Wang Y, Wei F, Tang Y, Li X, Liao Q, Wang H, Zhou M, Xiang B, Wu X, Li Y, Li X, Chen X, Li G, Guo C, Zeng Z, Xiong W
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):253
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):253
AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.
Zeng Z, Bo H, Gong Z, Lian Y, Li X, Li X, Zhang W, Deng H, Zhou M, Peng S, Li G, Xiong W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):729-37
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):729-37
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
Bo H, Gong Z, Zhang W, Li X, Zeng Y, Liao Q, Chen P, Shi L, Lian Y, Jing Y, Tang K, Li Z, Zhou Y, Zhou M, Xiang B, Li X, Yang J, Xiong W, Li G, Zeng Z
Oncotarget 2015 Aug 21;6(24):20404-18
Oncotarget 2015 Aug 21;6(24):20404-18
The molecular mechanism for effects of TiN coating on NiTi alloy on endothelial cell function.
Yang D, Lü X, Hong Y, Xi T, Zhang D
Biomaterials 2014 Aug;35(24):6195-205
Biomaterials 2014 Aug;35(24):6195-205
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 11680-1-AP(PFN1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Profilin 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Profilin 1. This antibody recognizes human,mouse,rat antigen. The Profilin 1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.