DPABH-23719

antibody from Creative Diagnostics

Targeting: PCDHB5 DKFZp586B0217, PCDH-BETA5

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DPABH-23719

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-23719, RRID:AB_2505631

Product name

Rabbit Anti-Human PCDHB5 Polyclonal antibody

Antibody type

Polyclonal

Description

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3 exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL