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Protein structure
LRR1
Leucine rich repeat protein 1LRR-1, MGC20689, PPIL5
The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
Top validated antibodies |
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| Proteintech Group |  11628-1-AP |
3 references | Polyclonal |
WB
EL
IHC
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| Atlas Antibodies | HPA069364 |
2 references | Polyclonal |
WB
ICC
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| NovoPro Bioscience Inc. | 112326 |
Polyclonal |
WB
EL
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA018486GA01HU |
Polyclonal |
WB
EL
IHC
|
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| FineTest Biotech | FNab04851 |
Polyclonal |
WB
EL
IHC
|
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