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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB16680 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB16680, RRID:AB_10698357
- Product name
- EBI3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of EBI3.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells.
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27.
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.
Niedbala W, Wei XQ, Cai B, Hueber AJ, Leung BP, McInnes IB, Liew FY
European journal of immunology 2007 Nov;37(11):3021-9
European journal of immunology 2007 Nov;37(11):3021-9
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27.
Pflanz S, Hibbert L, Mattson J, Rosales R, Vaisberg E, Bazan JF, Phillips JH, McClanahan TK, de Waal Malefyt R, Kastelein RA
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2225-31
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2225-31
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.
Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, Hibbert L, Churakova T, Travis M, Vaisberg E, Blumenschein WM, Mattson JD, Wagner JL, To W, Zurawski S, McClanahan TK, Gorman DM, Bazan JF, de Waal Malefyt R, Rennick D, Kastelein RA
Immunity 2002 Jun;16(6):779-90
Immunity 2002 Jun;16(6):779-90
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of EBI3 in K-562 cell lysate with EBI3 polyclonal antibody (Cat # PAB16680) at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of EBI3 in human spleen tissue with EBI3 polyclonal antibody (Cat # PAB16680) at 2.5 ug/mL .
- Validation comment
- Immunohistochemistry
