Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN499778 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Epstein-Barr Virus Induced 3 (EBI3) antibody
- Antibody type
- Polyclonal
- Antigen
- EBI3 antibody was raised against a 16 amino acid peptide from near the center of humanEBI3. (ABIN499777)
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Submitted references IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells.
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27.
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.
Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin.
Niedbala W, Wei XQ, Cai B, Hueber AJ, Leung BP, McInnes IB, Liew FY
European journal of immunology 2007 Nov;37(11):3021-9
European journal of immunology 2007 Nov;37(11):3021-9
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27.
Pflanz S, Hibbert L, Mattson J, Rosales R, Vaisberg E, Bazan JF, Phillips JH, McClanahan TK, de Waal Malefyt R, Kastelein RA
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2225-31
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2225-31
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.
Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, Hibbert L, Churakova T, Travis M, Vaisberg E, Blumenschein WM, Mattson JD, Wagner JL, To W, Zurawski S, McClanahan TK, Gorman DM, Bazan JF, de Waal Malefyt R, Rennick D, Kastelein RA
Immunity 2002 Jun;16(6):779-90
Immunity 2002 Jun;16(6):779-90
Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin.
Devergne O, Birkenbach M, Kieff E
Proceedings of the National Academy of Sciences of the United States of America 1997 Oct 28;94(22):12041-6
Proceedings of the National Academy of Sciences of the United States of America 1997 Oct 28;94(22):12041-6
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of EBI3 in rat spleen tissue lysate with AP30307PU-N EBI3 antibody at 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of EBI3 in human spleen tissue with AP30307PU-N EBI3 antibody at 2.5 ?g/ml.