NBP1-76701
antibody from Novus Biologicals
Targeting: HAVCR1
CD365, HAVCR, HAVCR-1, KIM1, TIM-1, TIM1, TIMD1
Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [5]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP1-76701 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-76701, RRID:AB_11037459
- Product name
- Rabbit Polyclonal TIM-1/KIM-1/HAVCR Antibody
- Antibody type
- Polyclonal
- Description
- Peptide affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Renal glycosuria as a novel early sign of colistin-induced kidney damage in mice.
Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies.
Modulatory effect of 4-phenyl butyric acid on hyperoxaluria-induced renal injury and inflammation.
Sema 3A as a biomarker of the activated mTOR pathway during hexavalent chromium-induced acute kidney injury.
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?
Heparin-based hydrogels induce human renal tubulogenesis in vitro.
Early involvement of cellular stress and inflammatory signals in the pathogenesis of tubulointerstitial kidney disease due to UMOD mutations.
Paracellular epithelial sodium transport maximizes energy efficiency in the kidney.
Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease.
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression.
Distinct role of matrix metalloproteinase-3 in kidney injury molecule-1 shedding by kidney proximal tubular epithelial cells.
Bβ(15-42) attenuates the effect of ischemia-reperfusion injury in renal transplantation.
Samodelov SL, Visentin M, Gai Z, Häusler S, Kullak-Ublick GA
Antimicrobial agents and chemotherapy 2019 Oct 7;63(12)
Antimicrobial agents and chemotherapy 2019 Oct 7;63(12)
Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies.
Kang HM, Lim JH, Noh KH, Park D, Cho HS, Susztak K, Jung CR
Scientific reports 2019 Nov 26;9(1):17610
Scientific reports 2019 Nov 26;9(1):17610
Modulatory effect of 4-phenyl butyric acid on hyperoxaluria-induced renal injury and inflammation.
Sharma M, Naura AS, Singla SK
Molecular and cellular biochemistry 2019 Jan;451(1-2):185-196
Molecular and cellular biochemistry 2019 Jan;451(1-2):185-196
Sema 3A as a biomarker of the activated mTOR pathway during hexavalent chromium-induced acute kidney injury.
Song MF, Yang Y, Yi ZW, Zhang ZQ, Shen XD, Hu GH, Zhu YF
Toxicology letters 2018 Dec 15;299:226-235
Toxicology letters 2018 Dec 15;299:226-235
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Qing X, Chinenov Y, Redecha P, Madaio M, Roelofs JJ, Farber G, Issuree PD, Donlin L, Mcllwain DR, Mak TW, Blobel CP, Salmon JE
The Journal of clinical investigation 2018 Apr 2;128(4):1397-1412
The Journal of clinical investigation 2018 Apr 2;128(4):1397-1412
Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?
Morrison MC, Yakala GK, Liang W, Wielinga PY, Salic K, van Koppen A, Tomar T, Kleemann R, Heeringa P, Kooistra T
Scientific reports 2017 Jun 6;7(1):2915
Scientific reports 2017 Jun 6;7(1):2915
Heparin-based hydrogels induce human renal tubulogenesis in vitro.
Weber HM, Tsurkan MV, Magno V, Freudenberg U, Werner C
Acta biomaterialia 2017 Jul 15;57:59-69
Acta biomaterialia 2017 Jul 15;57:59-69
Early involvement of cellular stress and inflammatory signals in the pathogenesis of tubulointerstitial kidney disease due to UMOD mutations.
Trudu M, Schaeffer C, Riba M, Ikehata M, Brambilla P, Messa P, Martinelli-Boneschi F, Rastaldi MP, Rampoldi L
Scientific reports 2017 Aug 7;7(1):7383
Scientific reports 2017 Aug 7;7(1):7383
Paracellular epithelial sodium transport maximizes energy efficiency in the kidney.
Pei L, Solis G, Nguyen MT, Kamat N, Magenheimer L, Zhuo M, Li J, Curry J, McDonough AA, Fields TA, Welch WJ, Yu AS
The Journal of clinical investigation 2016 Jul 1;126(7):2509-18
The Journal of clinical investigation 2016 Jul 1;126(7):2509-18
Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease.
Tang WH, Wang Z, Kennedy DJ, Wu Y, Buffa JA, Agatisa-Boyle B, Li XS, Levison BS, Hazen SL
Circulation research 2015 Jan 30;116(3):448-55
Circulation research 2015 Jan 30;116(3):448-55
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression.
Trudu M, Janas S, Lanzani C, Debaix H, Schaeffer C, Ikehata M, Citterio L, Demaretz S, Trevisani F, Ristagno G, Glaudemans B, Laghmani K, Dell'Antonio G, SKIPOGH team, Loffing J, Rastaldi MP, Manunta P, Devuyst O, Rampoldi L
Nature medicine 2013 Dec;19(12):1655-60
Nature medicine 2013 Dec;19(12):1655-60
Distinct role of matrix metalloproteinase-3 in kidney injury molecule-1 shedding by kidney proximal tubular epithelial cells.
Lim AI, Chan LY, Lai KN, Tang SC, Chow CW, Lam MF, Leung JC
The international journal of biochemistry & cell biology 2012 Jun;44(6):1040-50
The international journal of biochemistry & cell biology 2012 Jun;44(6):1040-50
Bβ(15-42) attenuates the effect of ischemia-reperfusion injury in renal transplantation.
Sörensen I, Rong S, Susnik N, Gueler F, Shushakova N, Albrecht M, Dittrich AM, von Vietinghoff S, Becker JU, Melk A, Bohlmann A, Reingruber S, Petzelbauer P, Haller H, Schmitt R
Journal of the American Society of Nephrology : JASN 2011 Oct;22(10):1887-96
Journal of the American Society of Nephrology : JASN 2011 Oct;22(10):1887-96
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TIM-1/KIM-1/HAVCR Antibody [NBP1-76701] - Analysis of TIM-1 in 3T3 cell lysate with TIM-1 antibody at 1 ug/mL.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TIM-1/KIM-1/HAVCR Antibody [NBP1-76701] - HeLa cells were transfected with control siRNAs (lane 1) or TIM-1 siRNAs (lane 2) Loading: 15 ug of HeLa whole cell lysates per lane. Antibodies: 3809 (8 ug/mL), 1 h incubation at RT in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TIM-1/KIM-1/HAVCR Antibody [NBP1-76701] - Loading: 15 ug of lysates per lane. Antibodies: TIM-1 3809 (8 ug/mL), overnight incubation at 4 C in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TIM-1/KIM-1/HAVCR Antibody [NBP1-76701] - Loading: 15 ug of NIH/3T3 cell lysates. Antibodies: TIM-1 3809 (8 ug/mL), overnight incubation at 4 C in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TIM-1/KIM-1/HAVCR Antibody [NBP1-76701] - Loading: 15 ug of lysates per lane. Antibodies: TIM-1 3809 (8 ug/mL), TIM-1 3811 (1 ug/mL), beta-actin (1 ug/mL), and GAPDH (0.02 ug/mL), overnight incubation at 4C (3809) or 1h incubation at RT in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TIM-1/KIM-1/HAVCR Antibody [NBP1-76701] - Human uterus tissue with TIM-1 antibody at 10 ug/ml.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TIM-1/KIM-1/HAVCR Antibody [NBP1-76701] - Analysis of human uterus tissue using anti-TIM-1 antibody (3809) at 10 ug/ml. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 h at RT; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody overnight at 4 C. A goat anti-rabbit IgG H&L (HRP) at 1/250 was used as secondary. Counter stained with Hematoxylin.