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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA007047 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA007047, RRID:AB_1078374
- Product name
- Anti-CDH6
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human CDH6, Gene description: cadherin 6, type 2, K-cadherin (fetal kidney), Validated applications: IHC, Uniprot ID: P55285, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape
Hnf4a Is Required for the Development of Cdh6-Expressing Progenitors into Proximal Tubules in the Mouse Kidney
β-catenin regulates the formation of multiple nephron segments in the mouse kidney
Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy
Cadherin 6 Is a New RUNX2 Target in TGF-β Signalling Pathway
Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney
Song L, Li Q, Xia L, Sahay A, Qiu Q, Li Y, Li H, Sasaki K, Susztak K, Wu H, Wan L
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Hnf4a Is Required for the Development of Cdh6-Expressing Progenitors into Proximal Tubules in the Mouse Kidney
Marable S, Chung E, Park J
Journal of the American Society of Nephrology 2020;31(11):2543-2558
Journal of the American Society of Nephrology 2020;31(11):2543-2558
β-catenin regulates the formation of multiple nephron segments in the mouse kidney
Deacon P, Concodora C, Chung E, Park J
Scientific Reports 2019;9(1)
Scientific Reports 2019;9(1)
Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy
Gugnoni M, Sancisi V, Gandolfi G, Manzotti G, Ragazzi M, Giordano D, Tamagnini I, Tigano M, Frasoldati A, Piana S, Ciarrocchi A
Oncogene 2016;36(5):667-677
Oncogene 2016;36(5):667-677
Cadherin 6 Is a New RUNX2 Target in TGF-β Signalling Pathway
Li J, Sancisi V, Gandolfi G, Ragazzi M, Nicoli D, Tamagnini I, Piana S, Ciarrocchi A
PLoS ONE 2013;8(9):e75489
PLoS ONE 2013;8(9):e75489
Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney
Takasato M, Er P, Becroft M, Vanslambrouck J, Stanley E, Elefanty A, Little M
Nature Cell Biology 2013;16(1):118-126
Nature Cell Biology 2013;16(1):118-126
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human kidney and lymph node tissues using HPA007047 antibody. Corresponding CDH6 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
