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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- 616502 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#616502, RRID:AB_10641709
- Product name
- Purified anti-HRF
- Antibody type
- Polyclonal
- Antigen
- GST- N-terminal HRF fusion protein
- Description
- HRF (histamine-releasing factor), also known as TCTP, TPT1, p02, and fortilin, is a member of the TCTP family of calcium-binding proteins. It is widely expressed and apparently serves as a transcriptional activator, calcium transporter, histamine inducer, and antiapoptotic, caspase-3 inhibitor. HRF, in addition to functioning as a histamine-releasing factor, can modulate secretion of cytokines from human basophils, eosinophils, T cells, B cells, and epithelial cells. HRF knockout mice were embryonic lethal. Transgenic mice models have shown that HRF augments the inflammatory response to allergens.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 200 µl
- Storage
- Upon receipt, store undiluted at -20°C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- HeLa (Lane 1) and A20 (Lane2) cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with polyclonal anti-HRF/N19 antibody. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and chemiluminescence detection.
- Conjugate
- Unconjugated
