Tissue expression
Cell line expression
Protein structure

PPM1F

Protein phosphatase, Mg2+/Mn2+ dependent 1F
CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2 
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
350 antibodies from 28 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Abnova Corporation
10 antibodies
Invitrogen Antibodies
9 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Atlas Antibodies
2 antibodies
Novus Biologicals
26 antibodies
antibodies-online
122 antibodies
Biorbyt
25 antibodies
NovoPro Bioscience Inc.
3 antibodies
OriGene
5 antibodies
Acris Antibodies GmbH
6 antibodies
Aviva Systems Biology
3 antibodies
GeneTex
2 antibodies
Abgent
2 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
RabMAbs
1 antibody
ProSci
2 antibodies
St John's Laboratory
1 antibody
Abbexa
9 antibodies
MyBioSource
4 antibodies
Boster Biological Technology
1 antibody
United States Biological
44 antibodies
Creative Diagnostics
3 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Leading Biology
2 antibodies
Creative Biolabs
5 antibodies