11920-1-AP
antibody from Proteintech Group
Targeting: IL1RL1
DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1
Antibody data
- Antibody Data
- Antigen structure
- References [34]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 11920-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11920-1-AP, RRID:AB_906359
- Product name
- ST2 antibody
- Antibody type
- Polyclonal
- Description
- ST2 antibody (Cat. #11920-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ultrasmall Nanoparticles Regulate Immune Microenvironment by Activating IL-33/ST2 to Alleviate Renal Ischemia-Reperfusion Injury.
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Alleviate Hypoxia-Induced Pulmonary Arterial Hypertension in Mice Via Macrophages.
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling.
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
Macrophage-derived inflammation promotes pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension mice.
Clinicopathological and Prognostic Relevance of Tumoral Suppression of Tumorigenicity 2 Expression in Patients With Surgically Resected Pancreatic Carcinoma.
Silencing of microRNA-106b-5p prevents doxorubicin-mediated cardiotoxicity through modulation of the PR55α/YY1/sST2 signaling axis.
THE IL-33/ST2 AXIS PROMOTES ACUTE RESPIRATORY DISTRESS SYNDROME BY NATURAL KILLER T CELLS.
IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.
Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats.
Multifunctional hydrogel modulates the immune microenvironment to improve allogeneic spinal cord tissue survival for complete spinal cord injury repair.
Effect of three clinical therapies on cytokines modulation in the hip articular cartilage and bone improvement in rat early osteonecrosis of the femoral head.
Crosstalk between Interleukin-1 Receptor-Like 1 and Transforming Growth Factor-β Receptor Signaling Promotes Renal Fibrosis.
Extracellular ATP accelerates cell death and decreases tight junction protein ZO-1 in hypoxic cochlear strial marginal cells in neonatal rats.
Quercetin Ameliorates Renal Injury and Pyroptosis in Lupus Nephritis through Inhibiting IL-33/ST2 Pathway In Vitro and In Vivo.
Differential expression of CD8 defines phenotypically distinct cytotoxic T cells in cancer and multiple sclerosis.
Circulating Soluble Suppression of Tumorigenicity 2 Predicts Recurrence After Radiofrequency Ablation of Persistent Atrial Fibrillation.
Extracorporeal Shockwave Therapy Modulates the Expressions of Proinflammatory Cytokines IL33 and IL17A, and Their Receptors ST2 and IL17RA, within the Articular Cartilage in Early Avascular Necrosis of the Femoral Head in a Rat Model.
Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3.
The miRNA199a/SIRT1/P300/Yy1/sST2 signaling axis regulates adverse cardiac remodeling following MI.
Osthole attenuates ovalbumin‑induced lung inflammation via the inhibition of IL‑33/ST2 signaling in asthmatic mice.
Helicobacter hepaticus infection-induced IL-33 promotes hepatic inflammation and fibrosis through ST2 signaling pathways in BALB/c mice.
Downregulated miR-524-5p Participates in the Tumor Microenvironment of Ameloblastoma by Targeting the Interleukin-33 (IL-33)/Suppression of Tumorigenicity 2 (ST2) Axis.
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Helicobacter pylori Induces IL-33 Production and Recruits ST-2 to Lipid Rafts to Exacerbate Inflammation.
Interleukin-33 prevents the development of autoimmune diabetes in NOD mice.
Yin-Yang 1 transcription factor modulates ST2 expression during adverse cardiac remodeling post-myocardial infarction.
Decreased ST2 expression is associated with gastric cancer progression and pathogenesis.
Increased Type 2 Innate Lymphoid Cells in Patients with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome.
Decreased IL-33 Production Contributes to Trophoblast Cell Dysfunction in Pregnancies with Preeclampsia.
IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-κB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation.
Pulmonary Production of Soluble ST2 in Heart Failure.
IL-33 activates tumor stroma to promote intestinal polyposis.
Interleukin-33 affects cytokine production by keratinocytes in vitiligo.
Xu L, Xing Z, Yuan J, Han Y, Jiang Z, Han M, Hou X, Xing W, Li Z
Advanced healthcare materials 2024 May;13(13):e2303276
Advanced healthcare materials 2024 May;13(13):e2303276
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Alleviate Hypoxia-Induced Pulmonary Arterial Hypertension in Mice Via Macrophages.
Liu H, Zhang Q, Liu C, Zhang Y, Wang Y, Huang P, Ma L, Ge R
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):329-345
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):329-345
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling.
Cadinu P, Sivanathan KN, Misra A, Xu RJ, Mangani D, Yang E, Rone JM, Tooley K, Kye YC, Bod L, Geistlinger L, Lee T, Mertens RT, Ono N, Wang G, Sanmarco L, Quintana FJ, Anderson AC, Kuchroo VK, Moffitt JR, Nowarski R
Cell 2024 Apr 11;187(8):2010-2028.e30
Cell 2024 Apr 11;187(8):2010-2028.e30
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
Wu Q, Liang Z, Jiang J, Feng X, Liu J, Zhang Z, Wang H, Wang N, Gou Y, Li Z, Cao Y
Cell death & disease 2023 Oct 11;14(10):668
Cell death & disease 2023 Oct 11;14(10):668
Macrophage-derived inflammation promotes pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension mice.
Liu H, Wang Y, Zhang Q, Liu C, Ma Y, Huang P, Ge R, Ma L
Immunology letters 2023 Nov;263:113-122
Immunology letters 2023 Nov;263:113-122
Clinicopathological and Prognostic Relevance of Tumoral Suppression of Tumorigenicity 2 Expression in Patients With Surgically Resected Pancreatic Carcinoma.
Nagase M, Ibuki E, Haba R, Okano K, Kadota K
Cancer diagnosis & prognosis 2023 May-Jun;3(3):311-319
Cancer diagnosis & prognosis 2023 May-Jun;3(3):311-319
Silencing of microRNA-106b-5p prevents doxorubicin-mediated cardiotoxicity through modulation of the PR55α/YY1/sST2 signaling axis.
Lax A, Soler F, Fernandez Del Palacio MJ, Pascual-Oliver S, Ballester MR, Fuster JJ, Pascual-Figal D, Asensio-Lopez MDC
Molecular therapy. Nucleic acids 2023 Jun 13;32:704-720
Molecular therapy. Nucleic acids 2023 Jun 13;32:704-720
THE IL-33/ST2 AXIS PROMOTES ACUTE RESPIRATORY DISTRESS SYNDROME BY NATURAL KILLER T CELLS.
Zou L, Dang W, Tao Y, Zhao H, Yang B, Xu X, Li Y
Shock (Augusta, Ga.) 2023 Jun 1;59(6):902-911
Shock (Augusta, Ga.) 2023 Jun 1;59(6):902-911
IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.
Li S, Liu H, Qian Y, Jiang L, Liu S, Liu Y, Liu C, Gu X
International immunopharmacology 2023 Jan;114:109479
International immunopharmacology 2023 Jan;114:109479
Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats.
Sitzia C, Vianello E, Dozio E, Kalousová M, Zima T, Brizzola S, Roccabianca P, Tedeschi G, Lamont J, Tacchini L, Corsi-Romanelli MM
International journal of molecular sciences 2023 Jan 19;24(3)
International journal of molecular sciences 2023 Jan 19;24(3)
Multifunctional hydrogel modulates the immune microenvironment to improve allogeneic spinal cord tissue survival for complete spinal cord injury repair.
Gao X, You Z, Li Y, Kang X, Yang W, Wang H, Zhang T, Zhao X, Sun Y, Shen H, Dai J
Acta biomaterialia 2023 Jan 1;155:235-246
Acta biomaterialia 2023 Jan 1;155:235-246
Effect of three clinical therapies on cytokines modulation in the hip articular cartilage and bone improvement in rat early osteonecrosis of the femoral head.
Hsu SL, Jhan SW, Hsu CC, Wu YN, Wu KLH, Kuo CA, Chiu HW, Cheng JH
Biomedical journal 2023 Dec;46(6):100571
Biomedical journal 2023 Dec;46(6):100571
Crosstalk between Interleukin-1 Receptor-Like 1 and Transforming Growth Factor-β Receptor Signaling Promotes Renal Fibrosis.
Zhu X, Lu J, Rao J, Ru D, Gao M, Shi D, Cao K, Wen S, Dai C, Wang X, Mi W, Liu L, Zhou H
The American journal of pathology 2023 Aug;193(8):1029-1045
The American journal of pathology 2023 Aug;193(8):1029-1045
Extracellular ATP accelerates cell death and decreases tight junction protein ZO-1 in hypoxic cochlear strial marginal cells in neonatal rats.
Zhao Y, Huang S, Xie R, Liu J
Cellular signalling 2023 Aug;108:110732
Cellular signalling 2023 Aug;108:110732
Quercetin Ameliorates Renal Injury and Pyroptosis in Lupus Nephritis through Inhibiting IL-33/ST2 Pathway In Vitro and In Vivo.
Chen HY, Chiang YF, Hong YH, Shieh TM, Huang TC, Ali M, Chang HY, Wang KL, Hsia SM
Antioxidants (Basel, Switzerland) 2022 Nov 13;11(11)
Antioxidants (Basel, Switzerland) 2022 Nov 13;11(11)
Differential expression of CD8 defines phenotypically distinct cytotoxic T cells in cancer and multiple sclerosis.
Burkard T, Herrero San Juan M, Dreis C, Kiprina A, Namgaladze D, Siebenbrodt K, Luger S, Foerch C, Pfeilschifter JM, Weigert A, Radeke HH
Clinical and translational medicine 2022 Dec;12(12):e1068
Clinical and translational medicine 2022 Dec;12(12):e1068
Circulating Soluble Suppression of Tumorigenicity 2 Predicts Recurrence After Radiofrequency Ablation of Persistent Atrial Fibrillation.
Tan R, Yu H, Han X, Liu Y, Yang X, Xia YL, Yin X
Frontiers in cardiovascular medicine 2021;8:653312
Frontiers in cardiovascular medicine 2021;8:653312
Extracorporeal Shockwave Therapy Modulates the Expressions of Proinflammatory Cytokines IL33 and IL17A, and Their Receptors ST2 and IL17RA, within the Articular Cartilage in Early Avascular Necrosis of the Femoral Head in a Rat Model.
Cheng JH, Jhan SW, Hsu CC, Chiu HW, Hsu SL
Mediators of inflammation 2021;2021:9915877
Mediators of inflammation 2021;2021:9915877
Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3.
Li HN, Yang QQ, Wang WT, Tian X, Feng F, Zhang ST, Xia YT, Wang JX, Zou YW, Wang JY, Zeng XY
Journal of neuroinflammation 2021 Jul 5;18(1):150
Journal of neuroinflammation 2021 Jul 5;18(1):150
The miRNA199a/SIRT1/P300/Yy1/sST2 signaling axis regulates adverse cardiac remodeling following MI.
Asensio-Lopez MC, Sassi Y, Soler F, Fernandez Del Palacio MJ, Pascual-Figal D, Lax A
Scientific reports 2021 Feb 16;11(1):3915
Scientific reports 2021 Feb 16;11(1):3915
Osthole attenuates ovalbumin‑induced lung inflammation via the inhibition of IL‑33/ST2 signaling in asthmatic mice.
Yang Q, Kong L, Huang W, Mohammadtursun N, Li X, Wang G, Wang L
International journal of molecular medicine 2020 Oct;46(4):1389-1398
International journal of molecular medicine 2020 Oct;46(4):1389-1398
Helicobacter hepaticus infection-induced IL-33 promotes hepatic inflammation and fibrosis through ST2 signaling pathways in BALB/c mice.
Cao S, Zhu L, Zhu C, Feng J, Yin J, Lu J, Xu Y, Yang H, Huang Y, Zhang Q
Biochemical and biophysical research communications 2020 May 7;525(3):654-661
Biochemical and biophysical research communications 2020 May 7;525(3):654-661
Downregulated miR-524-5p Participates in the Tumor Microenvironment of Ameloblastoma by Targeting the Interleukin-33 (IL-33)/Suppression of Tumorigenicity 2 (ST2) Axis.
Chen L, Wang G, Qiao X, Wang X, Liu J, Niu X, Zhong M
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 28;26:e921863
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 28;26:e921863
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, Chang X, Jin Z, Li J, Zhu Z, Liu B, Su L
Oncogene 2020 Feb;39(7):1414-1428
Oncogene 2020 Feb;39(7):1414-1428
Helicobacter pylori Induces IL-33 Production and Recruits ST-2 to Lipid Rafts to Exacerbate Inflammation.
Kuo CJ, Chen CY, Lo HR, Feng CL, Wu HY, Huang MZ, Liao TN, Chen YA, Lai CH
Cells 2019 Oct 21;8(10)
Cells 2019 Oct 21;8(10)
Interleukin-33 prevents the development of autoimmune diabetes in NOD mice.
Lu J, Liang Y, Zhao J, Meng H, Zhang X
International immunopharmacology 2019 May;70:9-15
International immunopharmacology 2019 May;70:9-15
Yin-Yang 1 transcription factor modulates ST2 expression during adverse cardiac remodeling post-myocardial infarction.
Asensio-Lopez MC, Lax A, Fernandez Del Palacio MJ, Sassi Y, Hajjar RJ, Januzzi JL, Bayes-Genis A, Pascual-Figal DA
Journal of molecular and cellular cardiology 2019 May;130:216-233
Journal of molecular and cellular cardiology 2019 May;130:216-233
Decreased ST2 expression is associated with gastric cancer progression and pathogenesis.
Bai F, Ba F, You Y, Feng Y, Tao W, Wu C, Jiu M, Nie Y
Oncology letters 2019 Jun;17(6):5761-5767
Oncology letters 2019 Jun;17(6):5761-5767
Increased Type 2 Innate Lymphoid Cells in Patients with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome.
Tsai YG, Liou JH, Hung SI, Chen CB, Chiu TM, Wang CW, Chung WH
The Journal of investigative dermatology 2019 Aug;139(8):1722-1731
The Journal of investigative dermatology 2019 Aug;139(8):1722-1731
Decreased IL-33 Production Contributes to Trophoblast Cell Dysfunction in Pregnancies with Preeclampsia.
Chen H, Zhou X, Han TL, Baker PN, Qi H, Zhang H
Mediators of inflammation 2018;2018:9787239
Mediators of inflammation 2018;2018:9787239
IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-κB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation.
Huang SJ, Yan JQ, Luo H, Zhou LY, Luo JG
Journal of neuroinflammation 2018 Jan 12;15(1):12
Journal of neuroinflammation 2018 Jan 12;15(1):12
Pulmonary Production of Soluble ST2 in Heart Failure.
Pascual-Figal DA, Pérez-Martínez MT, Asensio-Lopez MC, Sanchez-Más J, García-García ME, Martinez CM, Lencina M, Jara R, Januzzi JL, Lax A
Circulation. Heart failure 2018 Dec;11(12):e005488
Circulation. Heart failure 2018 Dec;11(12):e005488
IL-33 activates tumor stroma to promote intestinal polyposis.
Maywald RL, Doerner SK, Pastorelli L, De Salvo C, Benton SM, Dawson EP, Lanza DG, Berger NA, Markowitz SD, Lenz HJ, Nadeau JH, Pizarro TT, Heaney JD
Proceedings of the National Academy of Sciences of the United States of America 2015 May 12;112(19):E2487-96
Proceedings of the National Academy of Sciences of the United States of America 2015 May 12;112(19):E2487-96
Interleukin-33 affects cytokine production by keratinocytes in vitiligo.
Li P, Ma H, Han D, Mou K
Clinical and experimental dermatology 2015 Mar;40(2):163-70
Clinical and experimental dermatology 2015 Mar;40(2):163-70
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11920-1-AP(IL1RL1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ST2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ST2. This antibody recognizes human,mouse,rat antigen. The ST2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.