BS6110

antibody from Bioworld Technology, Inc
Targeting: MLST8 GbetaL, GBL, Lst8, Pop3
Provider product page for BS6110
Western blot
Immunohistochemistry

Antibody data

Product number
BS6110 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MLST8 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MLST8.
Description
Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MLST8 protein structure - BS6110 shown in red.